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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPM2A All Species: 4.55
Human Site: S98 Identified Species: 12.5
UniProt: O95278 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95278 NP_001018051.1 331 37158 S98 R E P G G E L S W E G N G P H
Chimpanzee Pan troglodytes XP_001161292 397 44862 V165 R W E P R G A V R L R P A G T
Rhesus Macaque Macaca mulatta XP_001087462 331 37203 S98 R E P G G E L S W E G N G P H
Dog Lupus familis XP_541139 300 33638 F67 G G N S I H S F S W S N G P H
Cat Felis silvestris
Mouse Mus musculus Q9WUA5 330 36959 H97 R E P G G E L H W E G N G P H
Rat Rattus norvegicus Q91XQ2 327 36624 H94 R E P G G E L H W E G N G P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506932 321 36298 V88 R F S P K Y S V W E G N G P H
Chicken Gallus gallus NP_001026240 319 36063 L85 R R E G G Q L L W E G N G P H
Frog Xenopus laevis NP_001085689 313 35944 I80 K K E A G A L I W E G N G P H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.4 98.1 72.2 N.A. 89.1 89.4 N.A. 66.1 74.3 67.3 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 64.4 98.4 77 N.A. 94.2 93.9 N.A. 72.5 85.1 81.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 26.6 N.A. 93.3 93.3 N.A. 53.3 73.3 60 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 26.6 N.A. 93.3 93.3 N.A. 53.3 80 73.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 12 12 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 45 34 0 0 45 0 0 0 78 0 0 0 0 0 % E
% Phe: 0 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 12 12 0 56 67 12 0 0 0 0 78 0 89 12 0 % G
% His: 0 0 0 0 0 12 0 23 0 0 0 0 0 0 89 % H
% Ile: 0 0 0 0 12 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 12 12 0 0 12 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 67 12 0 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 89 0 0 0 % N
% Pro: 0 0 45 23 0 0 0 0 0 0 0 12 0 89 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Q
% Arg: 78 12 0 0 12 0 0 0 12 0 12 0 0 0 0 % R
% Ser: 0 0 12 12 0 0 23 23 12 0 12 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % V
% Trp: 0 12 0 0 0 0 0 0 78 12 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _