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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK5
All Species:
17.88
Human Site:
S295
Identified Species:
35.76
UniProt:
O95279
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95279
NP_003731.1
499
55130
S295
V
N
I
F
S
F
L
S
K
K
E
E
T
Y
N
Chimpanzee
Pan troglodytes
XP_518449
499
55139
S295
V
N
I
F
S
F
L
S
K
K
E
E
T
Y
N
Rhesus Macaque
Macaca mulatta
XP_001117117
499
55089
S295
V
N
I
F
S
F
L
S
K
K
E
E
T
Y
N
Dog
Lupus familis
XP_538901
499
55165
S295
V
N
I
F
S
F
L
S
K
K
E
E
T
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
O88454
398
43033
E202
M
E
S
W
S
K
L
E
A
I
Y
F
V
I
V
Rat
Rattus norvegicus
Q9JIS4
538
59782
A312
L
V
G
L
A
Y
F
A
A
V
L
S
M
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507316
895
98135
N663
A
W
L
S
L
F
V
N
W
K
V
S
M
F
V
Chicken
Gallus gallus
XP_419478
484
55090
D284
L
Q
M
G
A
S
K
D
V
N
I
F
S
F
L
Frog
Xenopus laevis
Q63ZI0
374
42700
F178
L
C
I
G
A
A
A
F
S
H
Y
E
E
W
S
Zebra Danio
Brachydanio rerio
NP_001032478
513
57993
S295
V
N
I
F
S
F
L
S
K
K
K
E
G
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94526
1001
109271
N486
E
W
T
W
S
G
D
N
Q
Q
I
Q
E
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
N133
Q
S
I
G
E
R
M
N
T
F
A
A
K
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
89.9
N.A.
27.2
23.6
N.A.
38.7
69.1
21.4
50.4
N.A.
20.9
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
99
93.7
N.A.
44.4
42.1
N.A.
44
78.9
39.2
65.1
N.A.
31.6
N.A.
36
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
0
N.A.
13.3
0
13.3
86.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
40
33.3
40
93.3
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
25
9
9
9
17
0
9
9
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
0
9
0
0
9
0
0
34
50
17
0
0
% E
% Phe:
0
0
0
42
0
50
9
9
0
9
0
17
0
17
9
% F
% Gly:
0
0
9
25
0
9
0
0
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
59
0
0
0
0
0
0
9
17
0
0
17
0
% I
% Lys:
0
0
0
0
0
9
9
0
42
50
9
0
9
0
0
% K
% Leu:
25
0
9
9
9
0
50
0
0
0
9
0
0
9
17
% L
% Met:
9
0
9
0
0
0
9
0
0
0
0
0
17
0
0
% M
% Asn:
0
42
0
0
0
0
0
25
0
9
0
0
0
0
42
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
9
9
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
9
59
9
0
42
9
0
0
17
9
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
0
0
34
0
0
% T
% Val:
42
9
0
0
0
0
9
0
9
9
9
0
9
0
17
% V
% Trp:
0
17
0
17
0
0
0
0
9
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
17
0
0
42
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _