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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK5
All Species:
13.03
Human Site:
Y347
Identified Species:
26.06
UniProt:
O95279
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95279
NP_003731.1
499
55130
Y347
S
L
V
P
L
V
V
Y
S
K
N
R
V
P
T
Chimpanzee
Pan troglodytes
XP_518449
499
55139
Y347
S
L
V
P
L
V
V
Y
S
K
N
R
V
P
T
Rhesus Macaque
Macaca mulatta
XP_001117117
499
55089
Y347
S
L
A
P
L
V
V
Y
S
K
N
R
V
P
T
Dog
Lupus familis
XP_538901
499
55165
Y347
S
L
S
P
L
V
V
Y
S
K
N
R
M
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O88454
398
43033
V250
G
L
A
Y
F
A
S
V
L
T
T
I
G
N
W
Rat
Rattus norvegicus
Q9JIS4
538
59782
Q367
V
E
I
H
D
K
L
Q
R
A
A
T
I
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507316
895
98135
A744
E
A
G
T
G
P
E
A
A
G
S
G
P
P
G
Chicken
Gallus gallus
XP_419478
484
55090
D333
N
M
Q
N
A
I
K
D
A
Q
V
T
Y
T
K
Frog
Xenopus laevis
Q63ZI0
374
42700
M226
L
Y
V
A
F
S
F
M
Y
I
L
V
G
L
T
Zebra Danio
Brachydanio rerio
NP_001032478
513
57993
R354
V
S
L
D
G
S
P
R
L
K
R
H
Y
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94526
1001
109271
H753
I
R
A
L
E
V
V
H
T
H
A
V
L
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
E181
A
F
M
F
S
S
Y
E
N
W
T
Y
F
D
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.8
89.9
N.A.
27.2
23.6
N.A.
38.7
69.1
21.4
50.4
N.A.
20.9
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
99
93.7
N.A.
44.4
42.1
N.A.
44
78.9
39.2
65.1
N.A.
31.6
N.A.
36
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
6.6
0
N.A.
6.6
0
13.3
6.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
6.6
26.6
N.A.
20
33.3
13.3
13.3
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
25
9
9
9
0
9
17
9
17
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
9
0
0
0
0
0
17
0
% D
% Glu:
9
9
0
0
9
0
9
9
0
0
0
0
0
0
9
% E
% Phe:
0
9
0
9
17
0
9
0
0
0
0
0
9
0
9
% F
% Gly:
9
0
9
0
17
0
0
0
0
9
0
9
17
0
9
% G
% His:
0
0
0
9
0
0
0
9
0
9
0
9
0
0
0
% H
% Ile:
9
0
9
0
0
9
0
0
0
9
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
42
0
0
0
0
9
% K
% Leu:
9
42
9
9
34
0
9
0
17
0
9
0
9
9
0
% L
% Met:
0
9
9
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
9
0
34
0
0
9
0
% N
% Pro:
0
0
0
34
0
9
9
0
0
0
0
0
9
42
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
9
0
9
34
0
9
0
% R
% Ser:
34
9
9
0
9
25
9
0
34
0
9
0
0
9
17
% S
% Thr:
0
0
0
9
0
0
0
0
9
9
17
17
0
9
34
% T
% Val:
17
0
25
0
0
42
42
9
0
0
9
17
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% W
% Tyr:
0
9
0
9
0
0
9
34
9
0
0
9
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _