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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAPB
All Species:
33.03
Human Site:
S159
Identified Species:
66.06
UniProt:
O95292
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95292
NP_004729.1
243
27228
S159
I
V
S
K
S
L
S
S
S
L
D
D
T
E
V
Chimpanzee
Pan troglodytes
XP_001135371
233
26380
S150
M
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Rhesus Macaque
Macaca mulatta
XP_001085676
243
27212
S159
I
V
S
K
S
L
S
S
S
L
D
D
T
E
V
Dog
Lupus familis
XP_534466
243
27128
S159
T
V
S
K
A
L
S
S
S
L
D
D
T
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY76
243
26928
S159
A
A
A
K
S
L
T
S
P
L
D
D
T
E
V
Rat
Rattus norvegicus
Q9Z269
243
26898
S159
V
A
A
K
P
L
T
S
P
L
D
D
A
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511021
243
27315
S159
V
M
S
K
S
I
S
S
S
L
D
D
P
E
V
Chicken
Gallus gallus
NP_001006296
243
27255
S159
V
M
S
K
S
I
S
S
S
L
D
D
T
E
V
Frog
Xenopus laevis
NP_001088528
243
27333
S159
S
L
S
K
S
I
S
S
N
L
D
D
S
E
Y
Zebra Danio
Brachydanio rerio
NP_997812
243
27387
S158
L
S
M
K
S
M
A
S
S
M
D
D
G
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785910
241
26909
E159
T
V
P
Q
V
G
E
E
K
L
E
T
R
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40075
244
26907
P186
V
K
K
E
E
V
P
P
V
V
Q
K
T
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.6
99.5
96.3
N.A.
89.7
88.4
N.A.
92.1
87.2
76.9
74.9
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
74
99.5
97.1
N.A.
94.6
94.2
N.A.
95.4
94.2
88.8
88
N.A.
N.A.
N.A.
N.A.
67.4
P-Site Identity:
100
13.3
100
86.6
N.A.
66.6
53.3
N.A.
73.3
80
60
53.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
80
73.3
N.A.
93.3
100
86.6
80
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
0
9
0
9
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
84
75
0
9
0
% D
% Glu:
0
0
0
9
9
0
9
9
0
0
9
0
9
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
17
75
0
0
0
0
9
0
0
9
0
0
0
% K
% Leu:
9
9
0
0
0
42
0
0
9
75
0
0
0
0
9
% L
% Met:
9
17
9
0
0
9
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
9
9
9
9
0
9
9
17
0
0
0
9
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% R
% Ser:
9
9
50
0
59
9
50
84
50
0
0
0
9
0
0
% S
% Thr:
17
0
0
0
0
0
17
0
0
0
0
17
50
9
0
% T
% Val:
34
34
0
0
9
9
9
0
9
9
0
0
0
9
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _