Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAPB All Species: 21.52
Human Site: S160 Identified Species: 43.03
UniProt: O95292 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95292 NP_004729.1 243 27228 S160 V S K S L S S S L D D T E V K
Chimpanzee Pan troglodytes XP_001135371 233 26380 L151 P K P H S V S L N D T E T R K
Rhesus Macaque Macaca mulatta XP_001085676 243 27212 S160 V S K S L S S S L D D T E V K
Dog Lupus familis XP_534466 243 27128 S160 V S K A L S S S L D D T E V K
Cat Felis silvestris
Mouse Mus musculus Q9QY76 243 26928 P160 A A K S L T S P L D D T E V K
Rat Rattus norvegicus Q9Z269 243 26898 P160 A A K P L T S P L D D A E V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511021 243 27315 S160 M S K S I S S S L D D P E V K
Chicken Gallus gallus NP_001006296 243 27255 S160 M S K S I S S S L D D T E V K
Frog Xenopus laevis NP_001088528 243 27333 N160 L S K S I S S N L D D S E Y K
Zebra Danio Brachydanio rerio NP_997812 243 27387 S159 S M K S M A S S M D D G E V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785910 241 26909 K160 V P Q V G E E K L E T R D L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40075 244 26907 V187 K K E E V P P V V Q K T V P H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.6 99.5 96.3 N.A. 89.7 88.4 N.A. 92.1 87.2 76.9 74.9 N.A. N.A. N.A. N.A. 48.1
Protein Similarity: 100 74 99.5 97.1 N.A. 94.6 94.2 N.A. 95.4 94.2 88.8 88 N.A. N.A. N.A. N.A. 67.4
P-Site Identity: 100 20 100 93.3 N.A. 73.3 60 N.A. 80 86.6 66.6 60 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. 86.6 73.3 N.A. 93.3 100 93.3 80 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 0 9 0 9 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 84 75 0 9 0 9 % D
% Glu: 0 0 9 9 0 9 9 0 0 9 0 9 75 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 17 75 0 0 0 0 9 0 0 9 0 0 0 84 % K
% Leu: 9 0 0 0 42 0 0 9 75 0 0 0 0 9 0 % L
% Met: 17 9 0 0 9 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 9 9 9 9 0 9 9 17 0 0 0 9 0 9 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % R
% Ser: 9 50 0 59 9 50 84 50 0 0 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 17 0 0 0 0 17 50 9 0 0 % T
% Val: 34 0 0 9 9 9 0 9 9 0 0 0 9 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _