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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAPB
All Species:
30.3
Human Site:
S221
Identified Species:
60.61
UniProt:
O95292
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95292
NP_004729.1
243
27228
S221
T
G
K
E
E
G
L
S
T
R
L
L
A
L
V
Chimpanzee
Pan troglodytes
XP_001135371
233
26380
S210
S
F
R
D
N
V
T
S
P
L
P
S
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001085676
243
27212
S221
T
G
K
E
E
G
L
S
T
R
L
L
A
L
V
Dog
Lupus familis
XP_534466
243
27128
S221
A
G
K
E
E
G
L
S
A
R
L
L
A
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY76
243
26928
S221
T
G
K
E
E
G
L
S
A
R
L
L
A
L
V
Rat
Rattus norvegicus
Q9Z269
243
26898
S221
S
G
K
E
E
G
L
S
A
R
L
L
A
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511021
243
27315
S221
V
V
K
E
E
G
L
S
T
R
L
L
A
L
V
Chicken
Gallus gallus
NP_001006296
243
27255
S221
V
V
K
D
E
G
H
S
S
R
L
L
A
L
V
Frog
Xenopus laevis
NP_001088528
243
27333
N221
L
A
K
E
E
G
V
N
T
R
I
L
A
L
V
Zebra Danio
Brachydanio rerio
NP_997812
243
27387
S221
R
V
K
E
E
G
L
S
S
R
V
I
A
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785910
241
26909
M219
T
V
T
E
T
K
P
M
L
P
S
T
M
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40075
244
26907
I230
S
S
S
M
G
I
F
I
L
V
A
L
L
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.6
99.5
96.3
N.A.
89.7
88.4
N.A.
92.1
87.2
76.9
74.9
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
74
99.5
97.1
N.A.
94.6
94.2
N.A.
95.4
94.2
88.8
88
N.A.
N.A.
N.A.
N.A.
67.4
P-Site Identity:
100
20
100
86.6
N.A.
93.3
86.6
N.A.
86.6
66.6
66.6
60
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
86.6
N.A.
93.3
93.3
N.A.
86.6
80
86.6
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
25
0
9
0
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
75
75
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
0
0
9
75
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
0
0
9
9
0
17
17
% I
% Lys:
0
0
75
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
59
0
17
9
59
75
17
84
9
% L
% Met:
0
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
9
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
75
0
0
0
0
0
% R
% Ser:
25
9
9
0
0
0
0
75
17
0
9
9
0
0
0
% S
% Thr:
34
0
9
0
9
0
9
0
34
0
0
9
0
0
0
% T
% Val:
17
34
0
0
0
9
9
0
0
9
9
0
0
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _