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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAPB All Species: 23.33
Human Site: T164 Identified Species: 46.67
UniProt: O95292 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95292 NP_004729.1 243 27228 T164 L S S S L D D T E V K K V M E
Chimpanzee Pan troglodytes XP_001135371 233 26380 E155 S V S L N D T E T R K L M E E
Rhesus Macaque Macaca mulatta XP_001085676 243 27212 T164 L S S S L D D T E V K K V M E
Dog Lupus familis XP_534466 243 27128 T164 L S S S L D D T E V K K V M E
Cat Felis silvestris
Mouse Mus musculus Q9QY76 243 26928 T164 L T S P L D D T E V K K V M E
Rat Rattus norvegicus Q9Z269 243 26898 A164 L T S P L D D A E V K K V M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511021 243 27315 P164 I S S S L D D P E V K K V M E
Chicken Gallus gallus NP_001006296 243 27255 T164 I S S S L D D T E V K K V M E
Frog Xenopus laevis NP_001088528 243 27333 S164 I S S N L D D S E Y K K V A E
Zebra Danio Brachydanio rerio NP_997812 243 27387 G163 M A S S M D D G E V K K I M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785910 241 26909 R164 G E E K L E T R D L D T V V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40075 244 26907 T191 V P P V V Q K T V P H E N E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.6 99.5 96.3 N.A. 89.7 88.4 N.A. 92.1 87.2 76.9 74.9 N.A. N.A. N.A. N.A. 48.1
Protein Similarity: 100 74 99.5 97.1 N.A. 94.6 94.2 N.A. 95.4 94.2 88.8 88 N.A. N.A. N.A. N.A. 67.4
P-Site Identity: 100 26.6 100 100 N.A. 86.6 80 N.A. 86.6 93.3 66.6 66.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 86.6 N.A. 93.3 100 86.6 93.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 84 75 0 9 0 9 0 0 0 0 % D
% Glu: 0 9 9 0 0 9 0 9 75 0 0 9 0 17 84 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 25 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 9 0 0 9 0 0 0 84 75 0 0 17 % K
% Leu: 42 0 0 9 75 0 0 0 0 9 0 9 0 0 0 % L
% Met: 9 0 0 0 9 0 0 0 0 0 0 0 9 67 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 9 9 17 0 0 0 9 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % R
% Ser: 9 50 84 50 0 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 17 0 0 0 0 17 50 9 0 0 9 0 0 0 % T
% Val: 9 9 0 9 9 0 0 0 9 67 0 0 75 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _