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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGLS All Species: 35.15
Human Site: S101 Identified Species: 51.56
UniProt: O95336 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95336 NP_036220.1 258 27547 S101 L Y R T H L L S R L P I P E S
Chimpanzee Pan troglodytes XP_001173626 258 27538 S101 L Y R T H L L S R L P I P E S
Rhesus Macaque Macaca mulatta XP_001113729 258 27825 S101 L Y R T H L L S R L P I P E S
Dog Lupus familis XP_852582 362 39074 S205 L Y R T H L L S R L P I P D S
Cat Felis silvestris
Mouse Mus musculus Q9CQ60 257 27236 S101 L Y R T H L L S K L P I P D S
Rat Rattus norvegicus P85971 257 27216 S101 L Y R T H L L S K L P I P D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517951 261 27936 S104 Q Y R T H L L S K L P I P E S
Chicken Gallus gallus NP_001026759 250 26195 P93 A Y S A Q L L P W L P A P A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZ64 243 26653 T96 A Y R A E W L T Q L P C I Q E
Honey Bee Apis mellifera XP_624173 238 26246 G90 E Y K S N L I G K I P I T E D
Nematode Worm Caenorhab. elegans O18229 269 30395 N106 E Y L R L F P N E L R D V F V
Sea Urchin Strong. purpuratus XP_791905 245 26412 G92 I Y K E K L I G K T S L P E S
Poplar Tree Populus trichocarpa XP_002316080 266 29271 S102 L A K D G L L S K V P V V P S
Maize Zea mays NP_001151429 281 31307 A106 L T K E G F L A K V P I L N G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMX8 268 29868 S102 L A K D N L L S K V N V F P R
Baker's Yeast Sacchar. cerevisiae P38858 249 27766 D95 A F K R A V L D K L P S T S Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 85.6 68.7 N.A. 88.7 88.7 N.A. 79.3 69.3 N.A. N.A. N.A. 42.2 46.9 29.7 46.1
Protein Similarity: 100 99.6 89.5 70.4 N.A. 94.1 94.5 N.A. 85.4 78.2 N.A. N.A. N.A. 60 62 44.6 63.9
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 86.6 40 N.A. N.A. N.A. 33.3 33.3 13.3 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 40 N.A. N.A. N.A. 53.3 73.3 20 66.6
Percent
Protein Identity: 41.3 37 N.A. 37.6 36 N.A.
Protein Similarity: 59.7 55.1 N.A. 55.9 51.5 N.A.
P-Site Identity: 40 26.6 N.A. 26.6 20 N.A.
P-Site Similarity: 66.6 53.3 N.A. 60 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 13 0 13 7 0 0 7 0 0 0 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 13 0 0 0 7 0 0 0 7 0 19 7 % D
% Glu: 13 0 0 13 7 0 0 0 7 0 0 0 0 38 7 % E
% Phe: 0 7 0 0 0 13 0 0 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 0 13 0 0 13 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 13 0 0 7 0 57 7 0 0 % I
% Lys: 0 0 38 0 7 0 0 0 57 0 0 0 0 0 0 % K
% Leu: 57 0 7 0 7 75 82 0 0 69 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 0 0 7 0 0 7 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 7 7 0 0 82 0 57 13 7 % P
% Gln: 7 0 0 0 7 0 0 0 7 0 0 0 0 7 7 % Q
% Arg: 0 0 50 13 0 0 0 0 25 0 7 0 0 0 7 % R
% Ser: 0 0 7 7 0 0 0 57 0 0 7 7 0 7 57 % S
% Thr: 0 7 0 44 0 0 0 7 0 7 0 0 13 0 0 % T
% Val: 0 0 0 0 0 7 0 0 0 19 0 13 13 0 7 % V
% Trp: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _