Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGLS All Species: 33.03
Human Site: S108 Identified Species: 48.44
UniProt: O95336 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95336 NP_036220.1 258 27547 S108 S R L P I P E S Q V I T I N P
Chimpanzee Pan troglodytes XP_001173626 258 27538 S108 S R L P I P E S Q V I T I N P
Rhesus Macaque Macaca mulatta XP_001113729 258 27825 S108 S R L P I P E S Q V I T I N P
Dog Lupus familis XP_852582 362 39074 S212 S R L P I P D S Q V I T I N P
Cat Felis silvestris
Mouse Mus musculus Q9CQ60 257 27236 S108 S K L P I P D S Q V L T I N P
Rat Rattus norvegicus P85971 257 27216 S108 S K L P I P D S Q V L T I D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517951 261 27936 S111 S K L P I P E S Q V I T I N P
Chicken Gallus gallus NP_001026759 250 26195 P100 P W L P A P A P T V L A V A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZ64 243 26653 E103 T Q L P C I Q E S Q F V R A D
Honey Bee Apis mellifera XP_624173 238 26246 D97 G K I P I T E D Q F I K I N P
Nematode Worm Caenorhab. elegans O18229 269 30395 V113 N E L R D V F V P M Q I F K D
Sea Urchin Strong. purpuratus XP_791905 245 26412 S99 G K T S L P E S Q L Y G I K P
Poplar Tree Populus trichocarpa XP_002316080 266 29271 S109 S K V P V V P S H V N S I N D
Maize Zea mays NP_001151429 281 31307 G113 A K V P I L N G H V Y S I N D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMX8 268 29868 R109 S K V N V F P R H I C S I N D
Baker's Yeast Sacchar. cerevisiae P38858 249 27766 Q102 D K L P S T S Q P N V Y P M D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 85.6 68.7 N.A. 88.7 88.7 N.A. 79.3 69.3 N.A. N.A. N.A. 42.2 46.9 29.7 46.1
Protein Similarity: 100 99.6 89.5 70.4 N.A. 94.1 94.5 N.A. 85.4 78.2 N.A. N.A. N.A. 60 62 44.6 63.9
P-Site Identity: 100 100 100 93.3 N.A. 80 73.3 N.A. 93.3 33.3 N.A. N.A. N.A. 13.3 53.3 6.6 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 46.6 N.A. N.A. N.A. 33.3 66.6 20 60
Percent
Protein Identity: 41.3 37 N.A. 37.6 36 N.A.
Protein Similarity: 59.7 55.1 N.A. 55.9 51.5 N.A.
P-Site Identity: 40 33.3 N.A. 20 13.3 N.A.
P-Site Similarity: 66.6 60 N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 7 0 0 0 0 7 0 13 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 7 0 0 0 7 0 19 7 0 0 0 0 0 7 38 % D
% Glu: 0 7 0 0 0 0 38 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 7 0 0 7 7 0 7 0 0 % F
% Gly: 13 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 57 7 0 0 0 7 38 7 75 0 0 % I
% Lys: 0 57 0 0 0 0 0 0 0 0 0 7 0 13 0 % K
% Leu: 0 0 69 0 7 7 0 0 0 7 19 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % M
% Asn: 7 0 0 7 0 0 7 0 0 7 7 0 0 63 0 % N
% Pro: 7 0 0 82 0 57 13 7 13 0 0 0 7 0 63 % P
% Gln: 0 7 0 0 0 0 7 7 57 7 7 0 0 0 0 % Q
% Arg: 0 25 0 7 0 0 0 7 0 0 0 0 7 0 0 % R
% Ser: 57 0 0 7 7 0 7 57 7 0 0 19 0 0 0 % S
% Thr: 7 0 7 0 0 13 0 0 7 0 0 44 0 0 0 % T
% Val: 0 0 19 0 13 13 0 7 0 63 7 7 7 0 0 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 13 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _