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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGLS All Species: 46.67
Human Site: S46 Identified Species: 68.44
UniProt: O95336 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95336 NP_036220.1 258 27547 S46 A R F A L G L S G G S L V S M
Chimpanzee Pan troglodytes XP_001173626 258 27538 S46 A R F A L G L S G G S L V S M
Rhesus Macaque Macaca mulatta XP_001113729 258 27825 S46 A R F A L G L S G G S L V S M
Dog Lupus familis XP_852582 362 39074 S150 A R F A L G L S G G S L V S M
Cat Felis silvestris
Mouse Mus musculus Q9CQ60 257 27236 S46 G R F A L G L S G G S L V S M
Rat Rattus norvegicus P85971 257 27216 S46 G R F A L G L S G G S L V S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517951 261 27936 S49 G R F F L G V S G G S L V G L
Chicken Gallus gallus NP_001026759 250 26195 S38 G R F S L G L S G G S L V G L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZ64 243 26653 V43 A K H D K F S V G L S G G S L
Honey Bee Apis mellifera XP_624173 238 26246 T34 E A F A S S D T F K V G L S G
Nematode Worm Caenorhab. elegans O18229 269 30395 S53 G T V S I G V S G G S M P R V
Sea Urchin Strong. purpuratus XP_791905 245 26412 R33 S R S A I A A R G A F Y L G V
Poplar Tree Populus trichocarpa XP_002316080 266 29271 S49 G V F A I A I S G G S L I G L
Maize Zea mays NP_001151429 281 31307 S53 G Y F A I A L S G G P L V S F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMX8 268 29868 S49 G A F C I V L S G G S L I S F
Baker's Yeast Sacchar. cerevisiae P38858 249 27766 S40 S D F K V S V S G G S L I D A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 85.6 68.7 N.A. 88.7 88.7 N.A. 79.3 69.3 N.A. N.A. N.A. 42.2 46.9 29.7 46.1
Protein Similarity: 100 99.6 89.5 70.4 N.A. 94.1 94.5 N.A. 85.4 78.2 N.A. N.A. N.A. 60 62 44.6 63.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 66.6 73.3 N.A. N.A. N.A. 26.6 20 33.3 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 86.6 N.A. N.A. N.A. 40 33.3 66.6 46.6
Percent
Protein Identity: 41.3 37 N.A. 37.6 36 N.A.
Protein Similarity: 59.7 55.1 N.A. 55.9 51.5 N.A.
P-Site Identity: 46.6 60 N.A. 53.3 40 N.A.
P-Site Similarity: 73.3 66.6 N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 32 13 0 63 0 19 7 0 0 7 0 0 0 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 0 7 0 0 0 0 0 0 7 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 82 7 0 7 0 0 7 0 7 0 0 0 13 % F
% Gly: 50 0 0 0 0 57 0 0 94 82 0 13 7 25 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 32 0 7 0 0 0 0 0 19 0 0 % I
% Lys: 0 7 0 7 7 0 0 0 0 7 0 0 0 0 0 % K
% Leu: 0 0 0 0 50 0 57 0 0 7 0 75 13 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 38 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 57 0 0 0 0 0 7 0 0 0 0 0 7 0 % R
% Ser: 13 0 7 13 7 13 7 82 0 0 82 0 0 63 0 % S
% Thr: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % T
% Val: 0 7 7 0 7 7 19 7 0 0 7 0 57 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _