Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGLS All Species: 62.73
Human Site: T187 Identified Species: 92
UniProt: O95336 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95336 NP_036220.1 258 27547 T187 K P P P Q R V T L T L P V L N
Chimpanzee Pan troglodytes XP_001173626 258 27538 T187 K P P P Q R V T L T L P V L N
Rhesus Macaque Macaca mulatta XP_001113729 258 27825 T187 K P P P Q R V T L T L P V L N
Dog Lupus familis XP_852582 362 39074 T291 K P P P Q R V T L T L P V L N
Cat Felis silvestris
Mouse Mus musculus Q9CQ60 257 27236 T187 K P P P Q R V T L T L P V L N
Rat Rattus norvegicus P85971 257 27216 T187 K P P P Q R V T L T L P V L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517951 261 27936 T190 K P P P Q R V T L T L P V L N
Chicken Gallus gallus NP_001026759 250 26195 T179 K P P P Q R I T L T L P V L N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZ64 243 26653 T179 K P P P E R I T F T L P L I N
Honey Bee Apis mellifera XP_624173 238 26246 T176 K P P S S R I T F T L P V I N
Nematode Worm Caenorhab. elegans O18229 269 30395 T194 K P P P S R I T L T L Q T L Q
Sea Urchin Strong. purpuratus XP_791905 245 26412 T180 K P P P C R V T F T Y P V I N
Poplar Tree Populus trichocarpa XP_002316080 266 29271 T196 K P P P E R I T F T L P V I N
Maize Zea mays NP_001151429 281 31307 T200 Q P P P E R I T F T L P V I N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMX8 268 29868 T196 K P P P E R I T F T L P V I N
Baker's Yeast Sacchar. cerevisiae P38858 249 27766 T183 K P P S D R I T F T L P V L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 85.6 68.7 N.A. 88.7 88.7 N.A. 79.3 69.3 N.A. N.A. N.A. 42.2 46.9 29.7 46.1
Protein Similarity: 100 99.6 89.5 70.4 N.A. 94.1 94.5 N.A. 85.4 78.2 N.A. N.A. N.A. 60 62 44.6 63.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. N.A. 66.6 66.6 66.6 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 80 73.3 80
Percent
Protein Identity: 41.3 37 N.A. 37.6 36 N.A.
Protein Similarity: 59.7 55.1 N.A. 55.9 51.5 N.A.
P-Site Identity: 73.3 66.6 N.A. 73.3 66.6 N.A.
P-Site Similarity: 93.3 93.3 N.A. 93.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 44 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 50 0 0 0 0 0 0 38 0 % I
% Lys: 94 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 57 0 94 0 7 63 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 % N
% Pro: 0 100 100 88 0 0 0 0 0 0 0 94 0 0 0 % P
% Gln: 7 0 0 0 50 0 0 0 0 0 0 7 0 0 7 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 13 13 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 100 0 100 0 0 7 0 0 % T
% Val: 0 0 0 0 0 0 50 0 0 0 0 0 88 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _