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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGLS
All Species:
34.85
Human Site:
T249
Identified Species:
51.11
UniProt:
O95336
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95336
NP_036220.1
258
27547
T249
E
A
A
A
R
L
L
T
V
P
F
E
K
H
S
Chimpanzee
Pan troglodytes
XP_001173626
258
27538
T249
E
A
A
A
R
L
L
T
V
P
F
E
K
H
S
Rhesus Macaque
Macaca mulatta
XP_001113729
258
27825
T249
E
A
A
A
R
L
L
T
V
P
F
E
K
H
S
Dog
Lupus familis
XP_852582
362
39074
T353
E
A
A
A
R
L
L
T
V
P
F
E
K
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ60
257
27236
S248
E
A
A
A
R
L
L
S
V
P
F
E
K
H
S
Rat
Rattus norvegicus
P85971
257
27216
S248
E
A
A
A
R
L
L
S
V
P
F
E
K
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517951
261
27936
S252
E
P
A
A
K
L
L
S
V
P
F
E
K
H
S
Chicken
Gallus gallus
NP_001026759
250
26195
T241
E
A
A
A
K
E
L
T
V
P
F
E
K
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZ64
243
26653
A233
Q
L
T
L
I
V
D
A
G
A
G
K
E
I
E
Honey Bee
Apis mellifera
XP_624173
238
26246
Y224
Q
P
H
N
G
E
L
Y
W
I
L
D
E
A
A
Nematode Worm
Caenorhab. elegans
O18229
269
30395
P254
E
D
A
A
T
G
V
P
D
R
D
S
S
D
S
Sea Urchin
Strong. purpuratus
XP_791905
245
26412
H230
K
L
S
N
G
T
V
H
W
F
I
D
Q
P
A
Poplar Tree
Populus trichocarpa
XP_002316080
266
29271
W249
P
T
K
G
K
L
V
W
F
L
D
K
P
A
A
Maize
Zea mays
NP_001151429
281
31307
S268
A
A
A
S
F
L
D
S
K
N
D
D
D
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMX8
268
29868
W251
P
S
N
G
N
L
I
W
F
M
D
K
Q
A
G
Baker's Yeast
Sacchar. cerevisiae
P38858
249
27766
E238
K
T
S
W
F
V
N
E
E
A
F
G
K
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
85.6
68.7
N.A.
88.7
88.7
N.A.
79.3
69.3
N.A.
N.A.
N.A.
42.2
46.9
29.7
46.1
Protein Similarity:
100
99.6
89.5
70.4
N.A.
94.1
94.5
N.A.
85.4
78.2
N.A.
N.A.
N.A.
60
62
44.6
63.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
N.A.
N.A.
0
6.6
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
26.6
33.3
33.3
40
Percent
Protein Identity:
41.3
37
N.A.
37.6
36
N.A.
Protein Similarity:
59.7
55.1
N.A.
55.9
51.5
N.A.
P-Site Identity:
6.6
20
N.A.
6.6
13.3
N.A.
P-Site Similarity:
33.3
46.6
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
50
63
57
0
0
0
7
0
13
0
0
0
19
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
13
0
7
0
25
19
7
13
0
% D
% Glu:
57
0
0
0
0
13
0
7
7
0
0
50
13
0
7
% E
% Phe:
0
0
0
0
13
0
0
0
13
7
57
0
0
0
0
% F
% Gly:
0
0
0
13
13
7
0
0
7
0
7
7
0
0
7
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
7
7
0
0
7
0
% I
% Lys:
13
0
7
0
19
0
0
0
7
0
0
19
57
0
0
% K
% Leu:
0
13
0
7
0
63
57
0
0
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
13
7
0
7
0
0
7
0
0
0
0
0
% N
% Pro:
13
13
0
0
0
0
0
7
0
50
0
0
7
7
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
13
0
7
% Q
% Arg:
0
0
0
0
38
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
7
13
7
0
0
0
25
0
0
0
7
7
0
57
% S
% Thr:
0
13
7
0
7
7
0
32
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
13
19
0
50
0
0
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
13
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _