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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPSS2
All Species:
30
Human Site:
Y277
Identified Species:
66
UniProt:
O95340
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95340
NP_001015880.1
614
69501
Y277
G
F
M
R
E
K
E
Y
L
Q
V
M
H
F
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101994
614
69441
Y277
G
F
M
R
E
K
E
Y
L
Q
V
M
H
F
D
Dog
Lupus familis
XP_543589
673
75165
Y330
G
F
M
R
E
K
E
Y
L
Q
A
I
H
F
D
Cat
Felis silvestris
Mouse
Mus musculus
O88428
621
70272
Y278
G
F
M
R
E
K
E
Y
L
Q
T
L
H
F
D
Rat
Rattus norvegicus
NP_001099845
614
69393
Y276
G
F
M
R
E
K
E
Y
L
Q
T
L
H
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511666
625
70970
Y288
G
F
M
R
E
R
E
Y
L
Q
C
L
H
F
D
Chicken
Gallus gallus
XP_421557
609
68116
Y271
G
F
M
R
E
A
E
Y
L
Q
V
I
H
F
G
Frog
Xenopus laevis
NP_001083408
621
70201
Y272
G
F
M
R
E
R
E
Y
L
Q
V
L
H
F
D
Zebra Danio
Brachydanio rerio
NP_997727
614
69428
F276
G
F
M
R
E
R
E
F
L
Q
V
L
H
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001118238
652
73226
F315
G
F
M
R
E
R
E
F
L
Q
C
Q
H
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49196
293
31959
F14
R
A
S
R
P
S
V
F
C
S
I
P
G
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
86.1
N.A.
91.6
93
N.A.
76.3
85.9
82.1
81.2
N.A.
N.A.
N.A.
N.A.
64.7
Protein Similarity:
100
N.A.
99.6
89
N.A.
94.5
96.2
N.A.
86.8
93.1
89.2
92.6
N.A.
N.A.
N.A.
N.A.
76.8
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
80
80
86.6
73.3
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
100
93.3
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
19
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% D
% Glu:
0
0
0
0
91
0
91
0
0
0
0
0
0
0
0
% E
% Phe:
0
91
0
0
0
0
0
28
0
0
0
0
0
91
0
% F
% Gly:
91
0
0
0
0
0
0
0
0
0
0
0
10
0
28
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
19
0
0
0
% I
% Lys:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
91
0
0
46
0
10
0
% L
% Met:
0
0
91
0
0
0
0
0
0
0
0
19
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
91
0
10
0
0
0
% Q
% Arg:
10
0
0
100
0
37
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
46
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _