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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPSS2 All Species: 38.79
Human Site: Y434 Identified Species: 85.33
UniProt: O95340 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95340 NP_001015880.1 614 69501 Y434 R R L L E R G Y K H P V L L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001101994 614 69441 Y434 R R L L E R G Y K H P V L L L
Dog Lupus familis XP_543589 673 75165 Y492 R R L L D R G Y K Q P V L L L
Cat Felis silvestris
Mouse Mus musculus O88428 621 70272 Y440 R R L L E R G Y K H P V L L L
Rat Rattus norvegicus NP_001099845 614 69393 Y433 R R L L E R G Y K H P V L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511666 625 70970 Y445 R Q L L E R G Y R R P V L L L
Chicken Gallus gallus XP_421557 609 68116 Y428 R Q L L Q R G Y K N P V L L L
Frog Xenopus laevis NP_001083408 621 70201 Y440 R H L L S R G Y K C P V L L L
Zebra Danio Brachydanio rerio NP_997727 614 69428 Y433 R R L L D R G Y K K P V L L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001118238 652 73226 Y472 R R L K E R G Y K K P C L L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49196 293 31959 S136 S T V A C A L S K A L F E R G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 86.1 N.A. 91.6 93 N.A. 76.3 85.9 82.1 81.2 N.A. N.A. N.A. N.A. 64.7
Protein Similarity: 100 N.A. 99.6 89 N.A. 94.5 96.2 N.A. 86.8 93.1 89.2 92.6 N.A. N.A. N.A. N.A. 76.8
P-Site Identity: 100 N.A. 100 86.6 N.A. 100 100 N.A. 80 80 80 86.6 N.A. N.A. N.A. N.A. 80
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 93.3 100 80 93.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 30.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 10 0 10 0 0 0 % C
% Asp: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 55 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 91 0 0 0 0 0 0 0 10 % G
% His: 0 10 0 0 0 0 0 0 0 37 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 91 19 0 0 0 0 0 % K
% Leu: 0 0 91 82 0 0 10 0 0 0 10 0 91 91 91 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % P
% Gln: 0 19 0 0 10 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 91 64 0 0 0 91 0 0 10 10 0 0 0 10 0 % R
% Ser: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 82 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _