KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB11
All Species:
10.61
Human Site:
S1062
Identified Species:
21.21
UniProt:
O95342
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95342
NP_003733.2
1321
146407
S1062
L
D
R
Q
P
P
I
S
V
Y
N
T
A
G
E
Chimpanzee
Pan troglodytes
XP_526100
1321
146405
S1062
L
D
R
Q
P
P
I
S
V
Y
N
T
A
G
E
Rhesus Macaque
Macaca mulatta
XP_001097771
1223
135558
V994
F
S
Q
C
I
L
F
V
A
N
S
A
S
Y
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY30
1321
146658
D1062
L
D
R
K
P
P
I
D
V
Y
S
G
A
G
E
Rat
Rattus norvegicus
O70127
1321
146240
N1062
L
D
R
K
P
P
I
N
V
Y
S
E
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513897
1322
146482
S1063
M
D
R
H
P
R
I
S
T
Y
G
N
E
G
E
Chicken
Gallus gallus
XP_418636
1307
144961
D1046
F
E
R
V
P
L
I
D
S
Y
S
E
E
G
E
Frog
Xenopus laevis
NP_001081394
1287
141487
D1028
L
E
R
V
P
Q
I
D
S
Y
S
D
Q
G
E
Zebra Danio
Brachydanio rerio
XP_001923538
1297
143408
S1038
L
D
R
I
P
K
I
S
V
Y
S
K
D
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
Q1039
L
D
R
K
P
K
I
Q
S
P
M
G
T
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
D1062
L
R
K
I
S
K
I
D
S
L
S
L
A
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
D1016
I
D
R
K
S
K
I
D
S
S
D
E
T
G
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
89.1
N.A.
N.A.
81.9
82.4
N.A.
76.6
49.9
49.2
69.1
N.A.
38.5
N.A.
38.2
N.A.
Protein Similarity:
100
99.5
91.2
N.A.
N.A.
90.9
91.3
N.A.
88
68.5
68.1
81.9
N.A.
58.1
N.A.
58.2
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
73.3
73.3
N.A.
53.3
40
46.6
60
N.A.
33.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
86.6
93.3
N.A.
60
53.3
60
73.3
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
9
42
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
0
42
0
0
9
9
9
0
0
% D
% Glu:
0
17
0
0
0
0
0
0
0
0
0
25
17
0
67
% E
% Phe:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
17
0
84
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
17
9
0
92
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
9
34
0
34
0
0
0
0
0
9
0
0
9
% K
% Leu:
67
0
0
0
0
17
0
0
0
9
0
9
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
17
9
0
0
0
% N
% Pro:
0
0
0
0
75
34
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
9
17
0
9
0
9
0
0
0
0
9
0
9
% Q
% Arg:
0
9
84
0
0
9
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
9
0
0
17
0
0
34
42
9
59
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
17
17
0
9
% T
% Val:
0
0
0
17
0
0
0
9
42
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
67
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _