KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB11
All Species:
34.85
Human Site:
Y1176
Identified Species:
69.7
UniProt:
O95342
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95342
NP_003733.2
1321
146407
Y1176
S
I
M
D
N
I
K
Y
G
D
N
T
K
E
I
Chimpanzee
Pan troglodytes
XP_526100
1321
146405
Y1176
S
I
M
D
N
I
K
Y
G
D
N
T
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001097771
1223
135558
I1103
L
N
G
L
S
V
S
I
S
P
G
Q
T
L
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY30
1321
146658
Y1176
S
I
M
D
N
I
K
Y
G
D
N
T
K
E
I
Rat
Rattus norvegicus
O70127
1321
146240
Y1176
S
I
M
D
N
I
K
Y
G
D
N
T
K
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513897
1322
146482
Y1177
S
I
A
D
N
I
R
Y
G
D
N
T
Q
E
V
Chicken
Gallus gallus
XP_418636
1307
144961
Y1160
T
I
A
E
N
I
A
Y
G
D
N
S
R
E
V
Frog
Xenopus laevis
NP_001081394
1287
141487
Y1142
S
I
G
D
N
I
A
Y
G
D
N
N
R
K
V
Zebra Danio
Brachydanio rerio
XP_001923538
1297
143408
Y1152
S
I
A
E
N
I
R
Y
G
D
N
Q
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
A1157
R
S
I
A
E
N
I
A
Y
G
D
N
R
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
Y1175
S
I
A
E
N
I
I
Y
G
L
D
P
S
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FWX7
1278
137648
Y1130
T
I
R
A
N
I
A
Y
G
K
G
S
E
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
89.1
N.A.
N.A.
81.9
82.4
N.A.
76.6
49.9
49.2
69.1
N.A.
38.5
N.A.
38.2
N.A.
Protein Similarity:
100
99.5
91.2
N.A.
N.A.
90.9
91.3
N.A.
88
68.5
68.1
81.9
N.A.
58.1
N.A.
58.2
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
100
100
N.A.
73.3
53.3
60
60
N.A.
0
N.A.
40
N.A.
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
93.3
86.6
80
86.6
N.A.
20
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
17
0
0
25
9
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
0
0
0
0
67
17
0
0
0
0
% D
% Glu:
0
0
0
25
9
0
0
0
0
0
0
0
9
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
84
9
17
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
84
9
0
0
84
17
9
0
0
0
0
0
0
34
% I
% Lys:
0
0
0
0
0
0
34
0
0
9
0
0
34
9
0
% K
% Leu:
9
0
0
9
0
0
0
0
0
9
0
0
0
9
9
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
84
9
0
0
0
0
67
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% Q
% Arg:
9
0
9
0
0
0
17
0
0
0
0
0
34
9
0
% R
% Ser:
67
9
0
0
9
0
9
0
9
0
0
17
9
9
9
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
42
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _