KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC2
All Species:
54.85
Human Site:
Y67
Identified Species:
86.19
UniProt:
O95347
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95347
NP_001036015.1
1197
135656
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
A
G
I
Chimpanzee
Pan troglodytes
XP_001137286
1197
135653
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
A
G
I
Rhesus Macaque
Macaca mulatta
XP_001110075
1197
135674
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
A
G
I
Dog
Lupus familis
XP_538759
1191
134851
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
A
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG48
1191
134255
Y67
S
N
F
Q
D
L
V
Y
K
N
G
Q
A
G
I
Rat
Rattus norvegicus
P97690
1191
138430
E67
Q
R
L
A
L
L
H
E
G
T
G
P
R
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90988
1189
134923
Y67
S
S
L
Q
D
L
V
Y
K
N
G
Q
A
G
V
Frog
Xenopus laevis
P50533
1203
136323
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
A
G
I
Zebra Danio
Brachydanio rerio
NP_955836
1199
135278
Y67
T
N
L
Q
D
L
V
Y
K
N
G
L
A
G
I
Tiger Blowfish
Takifugu rubipres
NP_001027796
1200
135717
Y67
S
N
L
Q
D
L
V
Y
K
N
G
Q
G
G
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396284
1177
135689
Y67
T
S
L
Q
D
L
V
Y
K
S
G
Q
A
G
I
Nematode Worm
Caenorhab. elegans
Q09591
1244
140323
S67
K
S
M
H
E
L
I
S
H
G
G
T
K
A
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002304405
1176
132657
Y67
S
N
L
Q
E
L
V
Y
K
Q
G
Q
A
G
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN90
1171
132296
Y67
A
N
L
Q
E
L
V
Y
K
Q
G
Q
A
G
I
Baker's Yeast
Sacchar. cerevisiae
P38989
1170
133910
Y67
S
S
L
Q
D
L
I
Y
K
R
G
Q
A
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
95.4
N.A.
91.5
22.3
N.A.
N.A.
66.8
80.7
74.4
71.1
N.A.
47.9
32.7
N.A.
Protein Similarity:
100
99.7
99.5
97.5
N.A.
95.1
46.7
N.A.
N.A.
81.9
90.2
87.4
85.4
N.A.
70.2
54.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
86.6
100
86.6
93.3
N.A.
80
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
100
100
93.3
93.3
N.A.
100
46.6
N.A.
Percent
Protein Identity:
44.9
N.A.
N.A.
44.4
35.3
N.A.
Protein Similarity:
65.1
N.A.
N.A.
64.1
58.2
N.A.
P-Site Identity:
86.6
N.A.
N.A.
80
73.3
N.A.
P-Site Similarity:
93.3
N.A.
N.A.
93.3
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
0
0
0
0
80
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
20
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
7
100
0
7
87
0
% G
% His:
0
0
0
7
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
87
% I
% Lys:
7
0
0
0
0
0
0
0
87
0
0
0
7
0
0
% K
% Leu:
0
0
87
0
7
100
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
67
0
0
0
0
0
0
0
60
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
7
0
0
87
0
0
0
0
0
14
0
80
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
7
0
0
7
0
0
% R
% Ser:
67
27
0
0
0
0
0
7
0
7
0
0
0
0
0
% S
% Thr:
14
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
80
0
0
0
0
0
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _