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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FARS2 All Species: 9.7
Human Site: S18 Identified Species: 16.41
UniProt: O95363 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95363 NP_006558.1 451 52357 S18 H A Y V Y L V S K A S H I S R
Chimpanzee Pan troglodytes XP_518218 451 52446 S18 R A Y V Y L V S K A S H I S R
Rhesus Macaque Macaca mulatta XP_001096214 451 52244 S18 H A Y V Y L V S K A S H I S R
Dog Lupus familis XP_545326 515 58523 K102 M H V Y L V R K A S S V S K G
Cat Felis silvestris
Mouse Mus musculus Q99M01 451 52318 R18 Y E H I Y L V R K V S H A C R
Rat Rattus norvegicus Q6AYQ3 472 55146 R18 H E H L Y L V R K V S H V C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426039 449 52376 P20 Y S K T A L P P K I K V R G I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001099064 449 52086 A23 H I I R H C P A R V F S V S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16129 453 51978 R18 R H W L K S T R C L A S S A A
Honey Bee Apis mellifera XP_396590 421 49172 H24 N E I T L L G H K Y L T D N W
Nematode Worm Caenorhab. elegans NP_507852 458 52705 F19 R R C C T M L F Q K N A K S I
Sea Urchin Strong. purpuratus XP_785848 453 52655 H20 L H L K P A L H E L S R R C R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K73 429 49233 F29 N G F K R F S F V S S F S S S
Baker's Yeast Sacchar. cerevisiae P08425 469 54810 Y32 V E I N G I K Y K T D P Q T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 90.2 72.2 N.A. 85.1 82.4 N.A. N.A. 70.2 N.A. 64.5 N.A. 50.7 49.4 46.7 56.5
Protein Similarity: 100 99.3 92.9 77.8 N.A. 92 88.3 N.A. N.A. 82.2 N.A. 77.3 N.A. 68.6 67.6 64.4 73
P-Site Identity: 100 93.3 100 6.6 N.A. 46.6 53.3 N.A. N.A. 13.3 N.A. 20 N.A. 0 13.3 6.6 13.3
P-Site Similarity: 100 93.3 100 20 N.A. 66.6 73.3 N.A. N.A. 26.6 N.A. 46.6 N.A. 26.6 26.6 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 43 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 0 8 8 0 8 8 22 8 8 8 8 8 % A
% Cys: 0 0 8 8 0 8 0 0 8 0 0 0 0 22 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % D
% Glu: 0 29 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 15 0 0 8 8 0 0 0 % F
% Gly: 0 8 0 0 8 0 8 0 0 0 0 0 0 8 8 % G
% His: 29 22 15 0 8 0 0 15 0 0 0 36 0 0 0 % H
% Ile: 0 8 22 8 0 8 0 0 0 8 0 0 22 0 15 % I
% Lys: 0 0 8 15 8 0 8 8 58 8 8 0 8 8 0 % K
% Leu: 8 0 8 15 15 50 15 0 0 15 8 0 0 0 0 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 8 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 0 0 0 0 8 0 15 8 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % Q
% Arg: 22 8 0 8 8 0 8 22 8 0 0 8 15 0 50 % R
% Ser: 0 8 0 0 0 8 8 22 0 15 58 15 22 43 8 % S
% Thr: 0 0 0 15 8 0 8 0 0 8 0 8 0 8 8 % T
% Val: 8 0 8 22 0 8 36 0 8 22 0 15 15 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 15 0 22 8 36 0 0 8 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _