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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FARS2 All Species: 40.61
Human Site: T424 Identified Species: 68.72
UniProt: O95363 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95363 NP_006558.1 451 52357 T424 T Y R H M E R T L S Q R E V R
Chimpanzee Pan troglodytes XP_518218 451 52446 T424 T Y R H M E R T L S Q R E V R
Rhesus Macaque Macaca mulatta XP_001096214 451 52244 T424 T Y R H M E R T L S Q R E V R
Dog Lupus familis XP_545326 515 58523 T505 S T S S T L K T M E Q K Q V L
Cat Felis silvestris
Mouse Mus musculus Q99M01 451 52318 T424 T Y R H M E R T L S Q R E V G
Rat Rattus norvegicus Q6AYQ3 472 55146 T445 T Y R H M E R T L S Q R E V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426039 449 52376 T422 V Y R H P E R T L T Q N E V H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001099064 449 52086 T422 V Y R H M E R T L T Q E E V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16129 453 51978 T427 V Y R H M E R T L T Q A E V N
Honey Bee Apis mellifera XP_396590 421 49172 T394 I Y R D M E R T L S K R E V N
Nematode Worm Caenorhab. elegans NP_507852 458 52705 A432 V Y R S H E R A L T K E E V N
Sea Urchin Strong. purpuratus XP_785848 453 52655 T427 T Y R S M E R T L V R E E V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K73 429 49233 S403 V F R S M E R S L T D E E V N
Baker's Yeast Sacchar. cerevisiae P08425 469 54810 N443 N Y Q S M D R N L T N A E V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 90.2 72.2 N.A. 85.1 82.4 N.A. N.A. 70.2 N.A. 64.5 N.A. 50.7 49.4 46.7 56.5
Protein Similarity: 100 99.3 92.9 77.8 N.A. 92 88.3 N.A. N.A. 82.2 N.A. 77.3 N.A. 68.6 67.6 64.4 73
P-Site Identity: 100 100 100 20 N.A. 93.3 93.3 N.A. N.A. 66.6 N.A. 73.3 N.A. 73.3 73.3 46.6 66.6
P-Site Similarity: 100 100 100 53.3 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 80 N.A. 80 80 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. 43 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 86 0 0 0 8 0 29 93 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 58 8 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 15 8 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 0 93 0 0 0 0 0 8 % L
% Met: 0 0 0 0 79 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 8 8 0 0 36 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 65 0 8 0 0 % Q
% Arg: 0 0 86 0 0 0 93 0 0 0 8 43 0 0 22 % R
% Ser: 8 0 8 36 0 0 0 8 0 43 0 0 0 0 15 % S
% Thr: 43 8 0 0 8 0 0 79 0 43 0 0 0 0 0 % T
% Val: 36 0 0 0 0 0 0 0 0 8 0 0 0 100 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _