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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FARS2 All Species: 38.48
Human Site: Y144 Identified Species: 65.13
UniProt: O95363 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95363 NP_006558.1 451 52357 Y144 S R K K G D N Y Y L N R T H M
Chimpanzee Pan troglodytes XP_518218 451 52446 Y144 S R K K G D N Y Y L N R T H M
Rhesus Macaque Macaca mulatta XP_001096214 451 52244 Y144 S R K K G D N Y Y L N R T H M
Dog Lupus familis XP_545326 515 58523 Y228 S R K K G D N Y Y L N G N H M
Cat Felis silvestris
Mouse Mus musculus Q99M01 451 52318 Y144 S R K K G D N Y Y L N R A H M
Rat Rattus norvegicus Q6AYQ3 472 55146 Y144 S R K K G D N Y Y L N R G H M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426039 449 52376 Y142 S R R K E D N Y Y L N R D H M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001099064 449 52086 Y141 S C K K G E N Y Y L N R T H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16129 453 51978 Q134 D C Y Y I N Q Q H L L R A H T
Honey Bee Apis mellifera XP_396590 421 49172 L140 S M G L N N F L I I G D V Y R
Nematode Worm Caenorhab. elegans NP_507852 458 52705 Y143 S R R P S D T Y Y V N H E H C
Sea Urchin Strong. purpuratus XP_785848 453 52655 Y146 S R K K G D N Y Y I N E E F M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94K73 429 49233 Y150 S R S L N D T Y Y V D S Q T V
Baker's Yeast Sacchar. cerevisiae P08425 469 54810 F147 S D N I K S G F L I S A D V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 90.2 72.2 N.A. 85.1 82.4 N.A. N.A. 70.2 N.A. 64.5 N.A. 50.7 49.4 46.7 56.5
Protein Similarity: 100 99.3 92.9 77.8 N.A. 92 88.3 N.A. N.A. 82.2 N.A. 77.3 N.A. 68.6 67.6 64.4 73
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 80 N.A. 86.6 N.A. 20 6.6 46.6 73.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 93.3 N.A. 33.3 26.6 60 80
Percent
Protein Identity: N.A. N.A. N.A. 43 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 15 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 8 0 0 0 72 0 0 0 0 8 8 15 0 0 % D
% Glu: 0 0 0 0 8 8 0 0 0 0 0 8 15 0 0 % E
% Phe: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 58 0 8 0 0 0 8 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 72 0 % H
% Ile: 0 0 0 8 8 0 0 0 8 22 0 0 0 0 0 % I
% Lys: 0 0 58 65 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 15 0 0 0 8 8 65 8 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 65 % M
% Asn: 0 0 8 0 15 15 65 0 0 0 72 0 8 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % Q
% Arg: 0 72 15 0 0 0 0 0 0 0 0 58 0 0 8 % R
% Ser: 93 0 8 0 8 8 0 0 0 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 15 0 0 0 0 0 29 8 8 % T
% Val: 0 0 0 0 0 0 0 0 0 15 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 79 79 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _