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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FARS2
All Species:
31.52
Human Site:
Y382
Identified Species:
53.33
UniProt:
O95363
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95363
NP_006558.1
451
52357
Y382
N
Y
A
E
N
D
F
Y
D
L
V
R
T
I
G
Chimpanzee
Pan troglodytes
XP_518218
451
52446
Y382
N
Y
A
E
N
D
F
Y
D
L
V
R
T
I
G
Rhesus Macaque
Macaca mulatta
XP_001096214
451
52244
Y382
N
Y
A
E
N
D
F
Y
D
L
V
R
T
I
G
Dog
Lupus familis
XP_545326
515
58523
Y466
N
Y
T
E
N
D
F
Y
D
L
V
R
T
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99M01
451
52318
Y382
N
Y
T
E
N
D
F
Y
D
I
V
R
T
V
G
Rat
Rattus norvegicus
Q6AYQ3
472
55146
Y403
N
Y
T
E
N
D
F
Y
D
I
V
R
T
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426039
449
52376
Y380
T
Y
S
K
N
D
F
Y
D
L
A
R
S
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099064
449
52086
F380
G
Y
T
E
N
D
F
F
D
L
V
R
S
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16129
453
51978
S380
I
E
V
D
A
G
F
S
P
N
D
F
Y
D
L
Honey Bee
Apis mellifera
XP_396590
421
49172
F351
K
S
Y
S
S
K
N
F
Y
D
L
V
R
D
I
Nematode Worm
Caenorhab. elegans
NP_507852
458
52705
S387
V
Q
F
N
D
M
T
S
D
V
Y
D
T
I
R
Sea Urchin
Strong. purpuratus
XP_785848
453
52655
Y385
D
Y
E
S
N
D
F
Y
D
L
V
R
N
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94K73
429
49233
E362
F
T
E
N
N
F
C
E
V
V
R
G
I
A
G
Baker's Yeast
Sacchar. cerevisiae
P08425
469
54810
H396
K
P
D
I
H
Q
V
H
E
N
D
L
M
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
90.2
72.2
N.A.
85.1
82.4
N.A.
N.A.
70.2
N.A.
64.5
N.A.
50.7
49.4
46.7
56.5
Protein Similarity:
100
99.3
92.9
77.8
N.A.
92
88.3
N.A.
N.A.
82.2
N.A.
77.3
N.A.
68.6
67.6
64.4
73
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
60
N.A.
73.3
N.A.
6.6
0
20
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
86.6
N.A.
13.3
20
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
43
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.3
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
8
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
8
65
0
0
72
8
15
8
0
15
0
% D
% Glu:
0
8
15
50
0
0
0
8
8
0
0
0
0
8
0
% E
% Phe:
8
0
8
0
0
8
72
15
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
72
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
15
0
0
8
36
15
% I
% Lys:
15
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
50
8
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
43
0
0
15
72
0
8
0
0
15
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
65
8
0
8
% R
% Ser:
0
8
8
15
8
0
0
15
0
0
0
0
15
0
0
% S
% Thr:
8
8
29
0
0
0
8
0
0
0
0
0
50
0
0
% T
% Val:
8
0
8
0
0
0
8
0
8
15
58
8
0
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
65
8
0
0
0
0
58
8
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _