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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH2
All Species:
36.36
Human Site:
S436
Identified Species:
53.33
UniProt:
O95376
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95376
NP_006312.1
493
57819
S436
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Chimpanzee
Pan troglodytes
XP_001159720
493
57800
S436
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Rhesus Macaque
Macaca mulatta
XP_001096827
295
34031
N242
C
N
I
C
I
E
K
N
G
G
C
N
H
M
Q
Dog
Lupus familis
XP_533838
491
57469
S434
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K6
492
57678
S435
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Rat
Rattus norvegicus
NP_001012275
492
57722
S435
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505698
500
58727
S443
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Chicken
Gallus gallus
XP_414399
490
57300
S433
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Frog
Xenopus laevis
NP_001090245
492
57760
S435
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Zebra Danio
Brachydanio rerio
NP_998308
492
57435
S427
P
Y
A
Y
Y
M
E
S
G
P
R
K
K
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76924
509
58609
A450
P
Y
A
Y
Y
M
E
A
G
S
R
K
N
L
F
Honey Bee
Apis mellifera
XP_624643
488
56761
P431
P
Y
A
Y
Y
M
E
P
G
P
R
K
E
L
F
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
A426
P
F
A
Y
F
L
S
A
T
P
R
K
N
L
F
Sea Urchin
Strong. purpuratus
XP_001201925
751
84095
A386
P
Y
A
Y
F
M
D
A
G
P
R
K
K
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
E443
A
Y
G
Y
Y
L
P
E
H
E
H
A
K
R
Q
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
A479
A
V
A
Y
Y
S
D
A
S
H
N
L
T
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
53.3
98.5
N.A.
98.1
98.3
N.A.
93.4
93.3
91.2
80.7
N.A.
51.4
55.1
45
36.6
Protein Similarity:
100
100
55.7
99.5
N.A.
99.8
99.3
N.A.
96.1
96.5
96.3
88.6
N.A.
66
72.8
62.6
46.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
80
86.6
53.3
80
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
93.3
80
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
88
0
0
0
0
25
0
0
0
7
0
0
0
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
7
69
7
0
7
0
0
7
0
0
% E
% Phe:
0
7
0
0
13
0
0
0
0
0
0
0
0
0
82
% F
% Gly:
0
0
7
0
0
0
0
0
82
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
7
0
7
0
0
% H
% Ile:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
82
69
7
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
0
0
7
0
82
0
% L
% Met:
0
0
0
0
0
75
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
7
7
13
0
0
% N
% Pro:
82
0
0
0
0
0
7
7
0
75
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
82
0
0
7
0
% R
% Ser:
0
0
0
0
0
7
7
57
7
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
82
0
94
82
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _