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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH2
All Species:
49.09
Human Site:
S466
Identified Species:
72
UniProt:
O95376
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95376
NP_006312.1
493
57819
S466
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Chimpanzee
Pan troglodytes
XP_001159720
493
57800
S466
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Rhesus Macaque
Macaca mulatta
XP_001096827
295
34031
L272
P
S
G
T
F
L
W
L
G
L
R
Y
Y
L
S
Dog
Lupus familis
XP_533838
491
57469
S464
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K6
492
57678
S465
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Rat
Rattus norvegicus
NP_001012275
492
57722
S465
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505698
500
58727
S473
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Chicken
Gallus gallus
XP_414399
490
57300
S463
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Frog
Xenopus laevis
NP_001090245
492
57760
S465
W
K
V
E
R
A
D
S
Y
D
R
G
D
L
E
Zebra Danio
Brachydanio rerio
NP_998308
492
57435
T457
W
K
V
E
R
A
D
T
Y
E
R
G
E
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76924
509
58609
T480
W
K
I
E
R
A
E
T
T
D
L
G
D
L
E
Honey Bee
Apis mellifera
XP_624643
488
56761
T461
W
K
I
E
H
A
E
T
T
N
R
G
D
L
E
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
G456
W
A
V
E
R
A
D
G
T
A
R
G
A
L
E
Sea Urchin
Strong. purpuratus
XP_001201925
751
84095
T416
W
K
V
E
R
A
E
T
Y
D
R
G
V
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
D473
L
H
Q
C
V
E
K
D
L
V
Q
F
L
I
A
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
T509
S
E
L
L
Q
I
K
T
P
E
V
I
M
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
53.3
98.5
N.A.
98.1
98.3
N.A.
93.4
93.3
91.2
80.7
N.A.
51.4
55.1
45
36.6
Protein Similarity:
100
100
55.7
99.5
N.A.
99.8
99.3
N.A.
96.1
96.5
96.3
88.6
N.A.
66
72.8
62.6
46.7
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
66.6
N.A.
66.6
60
66.6
66.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
86.6
86.6
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
82
0
0
0
7
0
0
7
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
63
7
0
63
0
0
63
0
0
% D
% Glu:
0
7
0
82
0
7
19
0
0
13
0
0
7
0
69
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
7
0
0
82
0
0
0
% G
% His:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
7
0
0
0
0
0
7
0
7
0
% I
% Lys:
0
75
0
0
0
0
13
0
0
0
0
0
0
7
0
% K
% Leu:
7
0
7
7
0
7
0
7
7
7
7
0
7
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% P
% Gln:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
0
0
0
75
0
0
0
0
0
82
0
0
0
7
% R
% Ser:
7
7
0
0
0
0
0
50
0
0
0
0
0
7
13
% S
% Thr:
0
0
0
7
0
0
0
32
19
0
0
0
0
0
0
% T
% Val:
0
0
69
0
7
0
0
0
0
7
7
0
7
0
0
% V
% Trp:
82
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
63
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _