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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH2
All Species:
33.33
Human Site:
T65
Identified Species:
48.89
UniProt:
O95376
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95376
NP_006312.1
493
57819
T65
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
A
Chimpanzee
Pan troglodytes
XP_001159720
493
57800
T65
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001096827
295
34031
Dog
Lupus familis
XP_533838
491
57469
T63
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K6
492
57678
T64
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
A
Rat
Rattus norvegicus
NP_001012275
492
57722
T64
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505698
500
58727
T72
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
G
T
Chicken
Gallus gallus
XP_414399
490
57300
T63
E
Y
Q
F
T
C
L
T
Y
K
E
S
E
S
T
Frog
Xenopus laevis
NP_001090245
492
57760
T65
E
Y
Q
F
T
C
L
T
Y
R
E
S
E
S
A
Zebra Danio
Brachydanio rerio
NP_998308
492
57435
E59
F
N
C
L
T
Y
R
E
S
Q
R
V
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76924
509
58609
T73
L
N
T
I
L
Q
I
T
P
S
L
A
K
V
L
Honey Bee
Apis mellifera
XP_624643
488
56761
L65
I
E
E
V
E
R
L
L
N
E
D
V
E
L
L
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
I59
N
Q
V
E
R
V
F
I
D
G
V
N
S
L
V
Sea Urchin
Strong. purpuratus
XP_001201925
751
84095
I59
T
D
Q
D
I
A
N
I
L
V
E
T
G
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
R64
Q
K
N
F
C
V
L
R
E
E
D
I
R
R
H
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
T95
N
L
S
Y
E
C
L
T
T
K
G
I
F
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
53.3
98.5
N.A.
98.1
98.3
N.A.
93.4
93.3
91.2
80.7
N.A.
51.4
55.1
45
36.6
Protein Similarity:
100
100
55.7
99.5
N.A.
99.8
99.3
N.A.
96.1
96.5
96.3
88.6
N.A.
66
72.8
62.6
46.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
93.3
86.6
86.6
6.6
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
93.3
86.6
93.3
13.3
N.A.
26.6
33.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
38
% A
% Cys:
0
0
7
0
7
57
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
0
0
7
0
13
0
0
0
0
% D
% Glu:
50
7
7
7
13
0
0
7
7
13
57
0
57
7
7
% E
% Phe:
7
0
0
57
0
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
7
0
7
38
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
7
7
0
7
13
0
0
0
13
0
7
0
% I
% Lys:
0
7
0
0
0
0
0
0
0
50
0
0
7
0
0
% K
% Leu:
7
7
0
7
7
0
69
7
7
0
7
0
7
13
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
7
0
0
0
7
0
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
7
7
57
0
0
7
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
7
7
7
0
7
7
0
7
7
7
% R
% Ser:
0
0
7
0
0
0
0
0
7
7
0
50
7
13
0
% S
% Thr:
7
0
7
0
57
0
0
63
7
0
0
7
0
7
13
% T
% Val:
0
0
7
7
0
13
0
0
0
7
7
13
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
0
7
0
7
0
0
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _