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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH2
All Species:
50.3
Human Site:
Y337
Identified Species:
73.78
UniProt:
O95376
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95376
NP_006312.1
493
57819
Y337
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Chimpanzee
Pan troglodytes
XP_001159720
493
57800
Y337
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Rhesus Macaque
Macaca mulatta
XP_001096827
295
34031
Y145
N
E
E
L
R
E
K
Y
R
R
Y
L
F
R
D
Dog
Lupus familis
XP_533838
491
57469
Y335
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K6
492
57678
Y336
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Rat
Rattus norvegicus
NP_001012275
492
57722
Y336
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505698
500
58727
Y344
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Chicken
Gallus gallus
XP_414399
490
57300
Y334
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Frog
Xenopus laevis
NP_001090245
492
57760
Y336
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Zebra Danio
Brachydanio rerio
NP_998308
492
57435
Y328
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76924
509
58609
Y351
W
K
T
H
G
S
E
Y
Y
E
C
S
R
Y
K
Honey Bee
Apis mellifera
XP_624643
488
56761
Y332
W
K
A
H
G
S
E
Y
Y
V
C
S
R
Y
K
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
Y327
W
K
S
H
G
S
E
Y
Y
E
C
S
R
Y
K
Sea Urchin
Strong. purpuratus
XP_001201925
751
84095
E289
S
H
G
S
E
F
Y
E
C
S
R
Y
K
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
N343
T
G
G
F
Y
A
C
N
R
Y
E
V
A
K
Q
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
F381
W
A
P
H
G
K
N
F
F
Q
C
T
M
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
53.3
98.5
N.A.
98.1
98.3
N.A.
93.4
93.3
91.2
80.7
N.A.
51.4
55.1
45
36.6
Protein Similarity:
100
100
55.7
99.5
N.A.
99.8
99.3
N.A.
96.1
96.5
96.3
88.6
N.A.
66
72.8
62.6
46.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
86.6
93.3
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
86.6
100
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
7
0
82
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
7
7
0
7
7
75
7
0
69
7
0
0
7
0
% E
% Phe:
0
0
0
7
0
7
0
7
7
0
0
0
7
0
0
% F
% Gly:
0
7
13
0
82
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
82
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
75
0
0
0
7
7
0
0
0
0
0
7
7
82
% K
% Leu:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% Q
% Arg:
0
0
0
0
7
0
0
0
13
7
7
0
75
7
0
% R
% Ser:
7
0
7
7
0
75
0
0
0
7
0
75
0
0
0
% S
% Thr:
7
0
63
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
82
75
7
7
7
0
82
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _