KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH2
All Species:
35.15
Human Site:
Y386
Identified Species:
51.56
UniProt:
O95376
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95376
NP_006312.1
493
57819
Y386
L
Q
L
E
A
Q
T
Y
Q
R
I
H
E
K
I
Chimpanzee
Pan troglodytes
XP_001159720
493
57800
Y386
L
Q
L
E
A
Q
T
Y
Q
R
I
H
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001096827
295
34031
K194
C
N
E
V
F
C
F
K
C
R
Q
M
Y
H
A
Dog
Lupus familis
XP_533838
491
57469
Y384
L
Q
L
E
A
Q
T
Y
Q
R
I
H
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K6
492
57678
Y385
L
Q
L
E
A
Q
T
Y
E
R
I
H
E
K
I
Rat
Rattus norvegicus
NP_001012275
492
57722
Y385
L
Q
L
E
A
Q
T
Y
Q
R
I
H
E
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505698
500
58727
Y393
L
Q
L
E
A
Q
T
Y
Q
R
I
Q
E
K
I
Chicken
Gallus gallus
XP_414399
490
57300
Y383
L
Q
L
E
A
Q
T
Y
Q
R
I
Q
E
K
I
Frog
Xenopus laevis
NP_001090245
492
57760
Y385
L
Q
L
E
A
Q
T
Y
Q
Q
I
Q
E
K
I
Zebra Danio
Brachydanio rerio
NP_998308
492
57435
Y377
L
Q
L
E
A
Q
T
Y
Q
R
I
Q
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76924
509
58609
I400
L
K
L
E
Q
Q
T
I
D
R
L
R
Q
R
I
Honey Bee
Apis mellifera
XP_624643
488
56761
L381
L
K
L
E
E
Q
T
L
E
A
I
K
M
Q
I
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
R376
L
K
M
E
E
E
L
R
D
K
I
R
K
K
I
Sea Urchin
Strong. purpuratus
XP_001201925
751
84095
K338
L
E
A
Q
T
L
N
K
L
N
E
R
I
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
L392
R
Q
K
A
M
A
D
L
Q
Q
A
Q
M
Q
N
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
Q430
K
L
D
W
N
L
G
Q
T
L
G
T
K
V
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
53.3
98.5
N.A.
98.1
98.3
N.A.
93.4
93.3
91.2
80.7
N.A.
51.4
55.1
45
36.6
Protein Similarity:
100
100
55.7
99.5
N.A.
99.8
99.3
N.A.
96.1
96.5
96.3
88.6
N.A.
66
72.8
62.6
46.7
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
93.3
93.3
86.6
93.3
N.A.
46.6
46.6
33.3
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
73.3
66.6
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
57
7
0
0
0
7
7
0
0
0
7
% A
% Cys:
7
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
13
0
0
0
0
0
0
% D
% Glu:
0
7
7
75
13
7
0
0
13
0
7
0
57
0
7
% E
% Phe:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
32
0
7
7
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
69
0
7
0
75
% I
% Lys:
7
19
7
0
0
0
0
13
0
7
0
7
13
63
0
% K
% Leu:
82
7
69
0
0
13
7
13
7
7
7
0
0
0
0
% L
% Met:
0
0
7
0
7
0
0
0
0
0
0
7
13
0
0
% M
% Asn:
0
7
0
0
7
0
7
0
0
7
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
63
0
7
7
69
0
7
57
13
7
32
7
19
0
% Q
% Arg:
7
0
0
0
0
0
0
7
0
63
0
19
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
69
0
7
0
0
7
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _