Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARIH2 All Species: 47.58
Human Site: Y409 Identified Species: 69.78
UniProt: O95376 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95376 NP_006312.1 493 57819 Y409 G T W I D W Q Y L Q N A A K L
Chimpanzee Pan troglodytes XP_001159720 493 57800 Y409 G T W I D W Q Y L Q N A A K L
Rhesus Macaque Macaca mulatta XP_001096827 295 34031 C215 I R K W L T K C A D D S E T A
Dog Lupus familis XP_533838 491 57469 Y407 G T W I D W Q Y L Q N A A K L
Cat Felis silvestris
Mouse Mus musculus Q9Z1K6 492 57678 Y408 G T W I D W Q Y L Q N A A K L
Rat Rattus norvegicus NP_001012275 492 57722 Y408 G T W I D W Q Y L Q N A A K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505698 500 58727 Y416 G T W I D W Q Y L Q N A A K L
Chicken Gallus gallus XP_414399 490 57300 Y406 G T W I D W Q Y L Q N A A K L
Frog Xenopus laevis NP_001090245 492 57760 Y408 G T W I D W Q Y L Q N A A K L
Zebra Danio Brachydanio rerio NP_998308 492 57435 Y400 G T W I D W Q Y L Q N A A K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76924 509 58609 Y423 G T W I D W Q Y L F N A A A L
Honey Bee Apis mellifera XP_624643 488 56761 H404 G T W I D W Q H L F A A A S L
Nematode Worm Caenorhab. elegans Q22431 482 55789 Y399 G T W I D W Q Y L H K S V S L
Sea Urchin Strong. purpuratus XP_001201925 751 84095 Y359 G T W I D W Q Y L L D A A S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84RR0 562 63960 F416 T P E S Q L K F I L E A W L Q
Baker's Yeast Sacchar. cerevisiae P36113 551 63551 F452 I S W I D G Q F L S E S L K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 53.3 98.5 N.A. 98.1 98.3 N.A. 93.4 93.3 91.2 80.7 N.A. 51.4 55.1 45 36.6
Protein Similarity: 100 100 55.7 99.5 N.A. 99.8 99.3 N.A. 96.1 96.5 96.3 88.6 N.A. 66 72.8 62.6 46.7
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 73.3 66.6 80
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 80 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 26.8 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. 46.2 46.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 7 82 75 7 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 88 0 0 0 0 7 13 0 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 13 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 13 0 13 0 0 0 0 0 % F
% Gly: 82 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % H
% Ile: 13 0 0 88 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 0 0 13 0 0 0 7 0 0 63 0 % K
% Leu: 0 0 0 0 7 7 0 0 88 13 0 0 7 7 82 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 88 0 0 57 0 0 0 0 7 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 7 0 0 0 0 0 7 0 19 0 19 0 % S
% Thr: 7 82 0 0 0 7 0 0 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % V
% Trp: 0 0 88 7 0 82 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _