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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJB5
All Species:
13.33
Human Site:
S45
Identified Species:
32.59
UniProt:
O95377
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95377
NP_005259.1
273
31088
S45
V
T
A
E
R
V
W
S
D
D
H
K
D
F
D
Chimpanzee
Pan troglodytes
XP_001157007
471
53990
S45
V
T
A
E
R
V
W
S
D
D
H
K
D
F
D
Rhesus Macaque
Macaca mulatta
Q8MIT8
226
26206
I9
D
W
G
A
L
Q
T
I
L
G
G
V
N
K
Y
Dog
Lupus familis
XP_539605
273
30507
S45
V
T
A
E
R
V
W
S
D
D
H
K
D
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q02739
271
31176
G45
V
T
A
E
R
V
W
G
D
D
Q
K
D
F
D
Rat
Rattus norvegicus
P28232
271
31028
G45
V
T
A
E
R
V
W
G
D
D
Q
K
D
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507989
485
53471
S45
V
A
A
E
R
V
W
S
D
D
H
K
D
F
D
Chicken
Gallus gallus
O93533
263
30905
G45
V
A
A
E
R
V
W
G
D
E
Q
D
D
F
I
Frog
Xenopus laevis
P08983
264
29977
G45
A
A
A
E
S
V
W
G
D
E
K
S
A
F
T
Zebra Danio
Brachydanio rerio
O57474
381
43436
G46
T
A
V
E
S
A
W
G
D
E
Q
S
A
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
42.8
81.6
N.A.
76.9
75
N.A.
43.9
43.5
44.6
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.7
59.7
85.3
N.A.
85.3
85.7
N.A.
48.2
63.3
64.8
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
93.3
60
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
93.3
66.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
80
10
0
10
0
0
0
0
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
90
60
0
10
70
0
60
% D
% Glu:
0
0
0
90
0
0
0
0
0
30
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
90
0
% F
% Gly:
0
0
10
0
0
0
0
50
0
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
60
0
10
10
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
40
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
20
0
0
40
0
0
0
20
0
0
0
% S
% Thr:
10
50
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
70
0
10
0
0
80
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
90
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _