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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K6
All Species:
8.79
Human Site:
T490
Identified Species:
24.17
UniProt:
O95382
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95382
NP_004663.3
1288
142596
T490
L
Y
Q
H
F
R
P
T
P
E
P
P
G
G
P
Chimpanzee
Pan troglodytes
XP_513244
1288
142617
T490
L
Y
Q
H
F
R
P
T
P
E
P
P
G
G
P
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
M490
L
Y
Q
H
F
R
P
M
P
A
E
P
R
G
G
Dog
Lupus familis
XP_544471
1476
162831
M670
L
Y
Q
H
F
R
P
M
L
E
L
P
E
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTR2
1291
143036
T491
L
Y
Q
H
F
R
P
T
P
E
P
S
G
G
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
D464
I
W
H
V
L
P
D
D
K
K
G
I
Y
E
W
Chicken
Gallus gallus
XP_419725
1260
143069
V440
V
E
A
T
K
T
D
V
S
V
V
R
F
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
V514
I
Y
K
H
F
T
K
V
S
T
D
P
Q
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
F450
F
N
F
W
L
D
F
F
V
E
A
T
K
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.2
77.9
N.A.
87
N.A.
N.A.
46.5
46.4
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
39.4
Protein Similarity:
100
99.6
97.1
81
N.A.
91
N.A.
N.A.
62.8
63
N.A.
61.5
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
100
66.6
73.3
N.A.
93.3
N.A.
N.A.
0
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
66.6
73.3
N.A.
93.3
N.A.
N.A.
20
6.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
12
12
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
23
12
0
0
12
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
56
12
0
12
23
0
% E
% Phe:
12
0
12
0
67
0
12
12
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
34
56
12
% G
% His:
0
0
12
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
12
0
12
0
12
0
12
12
0
0
12
0
0
% K
% Leu:
56
0
0
0
23
0
0
0
12
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
56
0
45
0
34
56
0
12
56
% P
% Gln:
0
0
56
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
56
0
0
0
0
0
12
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
23
0
0
12
0
0
12
% S
% Thr:
0
0
0
12
0
23
0
34
0
12
0
12
0
0
0
% T
% Val:
12
0
0
12
0
0
0
23
12
12
12
0
0
0
12
% V
% Trp:
0
12
0
12
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
67
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _