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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF11
All Species:
24.24
Human Site:
S223
Identified Species:
53.33
UniProt:
O95390
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95390
NP_005802.1
407
45091
S223
R
R
H
I
R
I
R
S
L
K
I
E
L
H
S
Chimpanzee
Pan troglodytes
XP_509122
402
45460
S218
R
R
H
I
R
I
R
S
L
K
I
E
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001096135
279
31313
R103
L
K
I
E
L
H
S
R
S
G
H
W
Q
S
I
Dog
Lupus familis
XP_848358
267
30141
R91
L
K
I
E
L
H
S
R
S
G
H
W
Q
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1W4
405
44928
S221
R
R
H
I
R
I
R
S
L
K
I
E
L
H
S
Rat
Rattus norvegicus
Q9Z217
345
39075
S167
R
R
H
I
R
I
R
S
L
K
I
E
L
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506326
126
14515
Chicken
Gallus gallus
O42220
375
42689
S191
T
R
Y
T
G
I
R
S
L
K
L
D
M
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O42222
374
42057
S190
G
G
R
H
R
I
R
S
L
K
I
D
V
N
A
Tiger Blowfish
Takifugu rubipres
NP_001027844
376
42679
S192
N
R
H
I
R
I
R
S
L
K
L
D
V
K
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789990
426
48172
N242
T
K
L
R
L
V
A
N
I
K
V
Q
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
66.8
65.3
N.A.
99
83.5
N.A.
29.9
59.4
N.A.
58.7
59.2
N.A.
N.A.
N.A.
31.4
Protein Similarity:
100
89.4
67.5
65.5
N.A.
99
83.7
N.A.
30.9
74.4
N.A.
71.9
69.7
N.A.
N.A.
N.A.
51.6
P-Site Identity:
100
100
0
0
N.A.
100
100
N.A.
0
40
N.A.
46.6
60
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
6.6
N.A.
100
100
N.A.
0
73.3
N.A.
73.3
86.6
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
0
37
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
10
0
0
0
0
19
0
0
0
0
0
% G
% His:
0
0
46
10
0
19
0
0
0
0
19
0
0
37
0
% H
% Ile:
0
0
19
46
0
64
0
0
10
0
46
0
0
0
19
% I
% Lys:
0
28
0
0
0
0
0
0
0
73
0
0
0
10
0
% K
% Leu:
19
0
10
0
28
0
0
0
64
0
19
0
46
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% Q
% Arg:
37
55
10
10
55
0
64
19
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
64
19
0
0
0
0
28
37
% S
% Thr:
19
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _