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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF11
All Species:
26.67
Human Site:
Y336
Identified Species:
58.67
UniProt:
O95390
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95390
NP_005802.1
407
45091
Y336
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Chimpanzee
Pan troglodytes
XP_509122
402
45460
Y331
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Rhesus Macaque
Macaca mulatta
XP_001096135
279
31313
K209
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Q
Dog
Lupus familis
XP_848358
267
30141
K197
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1W4
405
44928
Y334
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Rat
Rattus norvegicus
Q9Z217
345
39075
I275
A
S
G
W
D
W
I
I
A
P
K
R
Y
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506326
126
14515
K56
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Q
Chicken
Gallus gallus
O42220
375
42689
Y304
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O42222
374
42057
Y303
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Tiger Blowfish
Takifugu rubipres
NP_001027844
376
42679
Y305
W
I
I
A
P
K
R
Y
K
A
N
Y
C
S
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789990
426
48172
Y355
W
I
I
A
P
R
T
Y
D
A
N
Y
C
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
66.8
65.3
N.A.
99
83.5
N.A.
29.9
59.4
N.A.
58.7
59.2
N.A.
N.A.
N.A.
31.4
Protein Similarity:
100
89.4
67.5
65.5
N.A.
99
83.7
N.A.
30.9
74.4
N.A.
71.9
69.7
N.A.
N.A.
N.A.
51.6
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
6.6
100
N.A.
100
100
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
0
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
64
0
0
0
0
37
64
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
28
64
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
28
64
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
28
91
64
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
28
55
0
28
55
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
28
64
0
0
0
0
% N
% Pro:
0
0
0
28
64
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% Q
% Arg:
0
0
0
0
0
37
55
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
0
28
64
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
64
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
28
64
0
0
28
64
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _