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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP10
All Species:
14.85
Human Site:
S257
Identified Species:
29.7
UniProt:
O95393
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95393
NP_055297.1
424
48047
S257
N
P
L
L
I
V
F
S
D
D
Q
S
S
D
K
Chimpanzee
Pan troglodytes
XP_525772
424
48047
S257
N
P
L
L
I
V
F
S
D
D
Q
S
S
D
K
Rhesus Macaque
Macaca mulatta
XP_001096299
424
47897
S257
N
P
L
L
I
V
F
S
D
D
Q
S
S
D
K
Dog
Lupus familis
XP_538528
424
48041
S257
V
P
L
L
V
V
F
S
D
D
Q
S
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R229
421
47870
V255
K
H
D
P
L
L
V
V
F
S
D
D
Q
S
N
Rat
Rattus norvegicus
Q4AEG6
421
47748
V255
K
H
D
P
L
L
V
V
F
S
D
D
Q
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518835
304
33502
D138
L
L
V
V
F
S
D
D
R
G
G
E
R
K
E
Chicken
Gallus gallus
P34822
427
48608
F259
N
L
P
L
L
I
V
F
S
N
D
R
S
N
G
Frog
Xenopus laevis
P30885
401
45970
I235
H
G
L
A
I
E
V
I
H
L
N
Q
T
K
T
Zebra Danio
Brachydanio rerio
P85857
404
46271
E238
R
H
S
R
T
Q
Q
E
R
A
I
L
V
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
V421
K
P
A
P
H
H
H
V
R
L
R
R
S
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
S229
H
V
E
L
M
S
T
S
G
N
N
R
R
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.8
91.5
N.A.
85.6
85.8
N.A.
46.7
44.2
33.9
28.5
N.A.
23.2
N.A.
N.A.
26.1
Protein Similarity:
100
100
98.3
95.2
N.A.
92.6
91.9
N.A.
55.4
64.1
48.8
43.8
N.A.
40.3
N.A.
N.A.
43.4
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
0
20
13.3
0
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
20
46.6
26.6
0
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
9
9
34
34
25
17
0
25
9
% D
% Glu:
0
0
9
0
0
9
0
9
0
0
0
9
0
9
9
% E
% Phe:
0
0
0
0
9
0
34
9
17
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
9
9
0
0
9
17
% G
% His:
17
25
0
0
9
9
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
9
0
9
0
0
9
0
0
0
0
% I
% Lys:
25
0
0
0
0
0
0
0
0
0
0
0
0
17
34
% K
% Leu:
9
17
42
50
25
17
0
0
0
17
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
0
0
0
0
17
17
0
0
9
9
% N
% Pro:
0
42
9
25
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
0
0
0
34
9
17
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
25
0
9
25
17
0
0
% R
% Ser:
0
0
9
0
0
17
0
42
9
17
0
34
50
17
9
% S
% Thr:
0
0
0
0
9
0
9
0
0
0
0
0
9
0
9
% T
% Val:
9
9
9
9
9
34
34
25
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _