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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS3 All Species: 21.21
Human Site: S292 Identified Species: 27.45
UniProt: O95396 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.12
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95396 NP_055299.1 460 49669 S292 F R S I R L R S R R L D C A A
Chimpanzee Pan troglodytes XP_514724 460 49607 S292 F R S I R L R S R R L D C A A
Rhesus Macaque Macaca mulatta XP_001093903 462 49786 S292 F R C I R L R S R R L D C A V
Dog Lupus familis XP_543052 458 49108 S290 F R C I Q L R S R R L D C A A
Cat Felis silvestris
Mouse Mus musculus A2BDX3 460 49356 R292 F R R I R L R R R R P D C V V
Rat Rattus norvegicus NP_001101274 458 49370 R290 F R R I R L R R R R P D C V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508929 397 41903 A256 L R L E G Q L A V F H H A G G
Chicken Gallus gallus XP_001232656 468 50801 P301 F R N I K L R P K K S D C A V
Frog Xenopus laevis Q58E95 451 49714 G286 F R N I K I R G K K N D C A A
Zebra Danio Brachydanio rerio Q8AWD2 459 50779 S292 F R S I R L R S R Q K E C V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLJ8 453 50220 S301 F R N I R I R S K R P N C H M
Honey Bee Apis mellifera XP_001120368 452 50498 A292 F R N I S L R A K N V N C V V
Nematode Worm Caenorhab. elegans O44510 402 44446 T261 E V C G D N P T I T A P I D Y
Sea Urchin Strong. purpuratus XP_786162 380 41626 S239 A D T V T N C S E G G V L G V
Poplar Tree Populus trichocarpa XP_002300327 460 50018 G296 I R I V K I R G R S L Q C E V
Maize Zea mays B6TNK6 468 50257 G311 I R V V K L R G S S P D C T H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZNW0 464 50555 G301 M R I V K I R G R S S Q C T V
Baker's Yeast Sacchar. cerevisiae P38820 440 49343 G281 L R T F K M R G R Q E K C L C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.1 91.5 N.A. 79.7 80.6 N.A. 52.8 64.3 58 60.8 N.A. 49.3 47.3 42.3 46
Protein Similarity: 100 99.7 96 95 N.A. 88 89.3 N.A. 62.8 77.9 73 77.8 N.A. 66.3 65.6 58 60.2
P-Site Identity: 100 100 86.6 86.6 N.A. 66.6 66.6 N.A. 6.6 53.3 53.3 66.6 N.A. 53.3 40 0 6.6
P-Site Similarity: 100 100 86.6 93.3 N.A. 66.6 66.6 N.A. 13.3 80 86.6 80 N.A. 80 73.3 6.6 20
Percent
Protein Identity: 44.1 45.3 N.A. 41.8 36.7 N.A.
Protein Similarity: 60.8 60.9 N.A. 61.6 55.8 N.A.
P-Site Identity: 33.3 33.3 N.A. 26.6 26.6 N.A.
P-Site Similarity: 53.3 46.6 N.A. 46.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 12 0 0 6 0 6 34 23 % A
% Cys: 0 0 17 0 0 0 6 0 0 0 0 0 84 0 6 % C
% Asp: 0 6 0 0 6 0 0 0 0 0 0 50 0 6 0 % D
% Glu: 6 0 0 6 0 0 0 0 6 0 6 6 0 6 0 % E
% Phe: 62 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % F
% Gly: 0 0 0 6 6 0 0 28 0 6 6 0 0 12 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 6 6 0 6 6 % H
% Ile: 12 0 12 62 0 23 0 0 6 0 0 0 6 0 0 % I
% Lys: 0 0 0 0 34 0 0 0 23 12 6 6 0 0 0 % K
% Leu: 12 0 6 0 0 56 6 0 0 0 28 0 6 6 0 % L
% Met: 6 0 0 0 0 6 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 23 0 0 12 0 0 0 6 6 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 6 6 0 0 23 6 0 0 0 % P
% Gln: 0 0 0 0 6 6 0 0 0 12 0 12 0 0 0 % Q
% Arg: 0 89 12 0 39 0 84 12 56 39 0 0 0 0 0 % R
% Ser: 0 0 17 0 6 0 0 39 6 17 12 0 0 0 0 % S
% Thr: 0 0 12 0 6 0 0 6 0 6 0 0 0 12 0 % T
% Val: 0 6 6 23 0 0 0 0 6 0 6 6 0 23 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _