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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS3 All Species: 23.33
Human Site: S385 Identified Species: 30.2
UniProt: O95396 Number Species: 17
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95396 NP_055299.1 460 49669 S385 L E R R D A E S L K L L K E A
Chimpanzee Pan troglodytes XP_514724 460 49607 S385 L E R R D A E S L K L L K E A
Rhesus Macaque Macaca mulatta XP_001093903 462 49786 S385 L E R R D G E S L K L L K E A
Dog Lupus familis XP_543052 458 49108 S383 L E R R N A E S L K L L G E A
Cat Felis silvestris
Mouse Mus musculus A2BDX3 460 49356 S385 L E R R D A D S L K L L G A A
Rat Rattus norvegicus NP_001101274 458 49370 S383 L E R R D A D S L K L L G A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508929 397 41903 G326 L L F D A L G G H F H S I R I
Chicken Gallus gallus XP_001232656 468 50801 C394 L E E K D E E C M E Y L E K I
Frog Xenopus laevis Q58E95 451 49714 S364 D I C R L P H S I H I P L K G
Zebra Danio Brachydanio rerio Q8AWD2 459 50779 H385 L E D K K P E H I T L L K E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLJ8 453 50220 A378 E I C Q L P E A V N V P L V E
Honey Bee Apis mellifera XP_001120368 452 50498 N380 I P L N D I N N D E K I N F I
Nematode Worm Caenorhab. elegans O44510 402 44446 K331 E A I N V T L K E C R S L S A
Sea Urchin Strong. purpuratus XP_786162 380 41626 I309 N P S V T Q L I D Y E E F C G
Poplar Tree Populus trichocarpa XP_002300327 460 50018 S385 A M N I P L S S L E S R L A E
Maize Zea mays B6TNK6 468 50257 P393 F Q I A S I S P S H N I P L S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZNW0 464 50555 L389 L N I P L A N L E T R L N E L
Baker's Yeast Sacchar. cerevisiae P38820 440 49343 P366 F P E A V N I P I K N L R D M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.1 91.5 N.A. 79.7 80.6 N.A. 52.8 64.3 58 60.8 N.A. 49.3 47.3 42.3 46
Protein Similarity: 100 99.7 96 95 N.A. 88 89.3 N.A. 62.8 77.9 73 77.8 N.A. 66.3 65.6 58 60.2
P-Site Identity: 100 100 93.3 86.6 N.A. 80 80 N.A. 6.6 33.3 13.3 53.3 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 6.6 66.6 33.3 66.6 N.A. 33.3 33.3 6.6 0
Percent
Protein Identity: 44.1 45.3 N.A. 41.8 36.7 N.A.
Protein Similarity: 60.8 60.9 N.A. 61.6 55.8 N.A.
P-Site Identity: 13.3 0 N.A. 26.6 13.3 N.A.
P-Site Similarity: 20 20 N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 12 6 34 0 6 0 0 0 0 0 17 45 % A
% Cys: 0 0 12 0 0 0 0 6 0 6 0 0 0 6 0 % C
% Asp: 6 0 6 6 39 0 12 0 12 0 0 0 0 6 0 % D
% Glu: 12 45 12 0 0 6 39 0 12 17 6 6 6 34 12 % E
% Phe: 12 0 6 0 0 0 0 0 0 6 0 0 6 6 0 % F
% Gly: 0 0 0 0 0 6 6 6 0 0 0 0 17 0 12 % G
% His: 0 0 0 0 0 0 6 6 6 12 6 0 0 0 0 % H
% Ile: 6 12 17 6 0 12 6 6 17 0 6 12 6 0 17 % I
% Lys: 0 0 0 12 6 0 0 6 0 39 6 0 23 12 0 % K
% Leu: 56 6 6 0 17 12 12 6 39 0 39 56 23 6 6 % L
% Met: 0 6 0 0 0 0 0 0 6 0 0 0 0 0 6 % M
% Asn: 6 6 6 12 6 6 12 6 0 6 12 0 12 0 0 % N
% Pro: 0 17 0 6 6 17 0 12 0 0 0 12 6 0 0 % P
% Gln: 0 6 0 6 0 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 34 39 0 0 0 0 0 0 12 6 6 6 0 % R
% Ser: 0 0 6 0 6 0 12 45 6 0 6 12 0 6 6 % S
% Thr: 0 0 0 0 6 6 0 0 0 12 0 0 0 0 0 % T
% Val: 0 0 0 6 12 0 0 0 6 0 6 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 6 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _