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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS3 All Species: 18.18
Human Site: T400 Identified Species: 23.53
UniProt: O95396 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95396 NP_055299.1 460 49669 T400 I W E E K Q G T Q E G A A V P
Chimpanzee Pan troglodytes XP_514724 460 49607 T400 I W E E K Q G T Q E G A A V P
Rhesus Macaque Macaca mulatta XP_001093903 462 49786 T400 I W E G K Q G T Q E E A A V P
Dog Lupus familis XP_543052 458 49108 A398 I R E G K Q G A Q A G A A F P
Cat Felis silvestris
Mouse Mus musculus A2BDX3 460 49356 S400 L R K G K Q E S Q E G V A L P
Rat Rattus norvegicus NP_001101274 458 49370 S398 L Q E E K R N S Q E G A A L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508929 397 41903 P341 S G P L T N Q P P A E F R H W
Chicken Gallus gallus XP_001232656 468 50801 T409 I F E E K Q R T D G Q T S F P
Frog Xenopus laevis Q58E95 451 49714 W379 L E E K N E K W V S F L R T K
Zebra Danio Brachydanio rerio Q8AWD2 459 50779 L400 I S D L Q E H L N N Q S P V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLJ8 453 50220 K393 I L D D S Y L K R L G K Q L E
Honey Bee Apis mellifera XP_001120368 452 50498 Q395 K N K I E E M Q K Q Y D K T T
Nematode Worm Caenorhab. elegans O44510 402 44446 G346 E D I S N R L G L Q N T E H S
Sea Urchin Strong. purpuratus XP_786162 380 41626 I324 A S A T D K C I T L H L L E A
Poplar Tree Populus trichocarpa XP_002300327 460 50018 E400 I S S A L K E E E K R K D S G
Maize Zea mays B6TNK6 468 50257 A408 M L E E K L P A L E A S L K E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZNW0 464 50555 G404 T S A L K E K G N G H A N T E
Baker's Yeast Sacchar. cerevisiae P38820 440 49343 Q381 N G D L K K L Q E K L P S V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.1 91.5 N.A. 79.7 80.6 N.A. 52.8 64.3 58 60.8 N.A. 49.3 47.3 42.3 46
Protein Similarity: 100 99.7 96 95 N.A. 88 89.3 N.A. 62.8 77.9 73 77.8 N.A. 66.3 65.6 58 60.2
P-Site Identity: 100 100 86.6 66.6 N.A. 46.6 53.3 N.A. 0 46.6 6.6 13.3 N.A. 13.3 0 0 0
P-Site Similarity: 100 100 86.6 66.6 N.A. 73.3 80 N.A. 0 60 26.6 40 N.A. 40 33.3 13.3 6.6
Percent
Protein Identity: 44.1 45.3 N.A. 41.8 36.7 N.A.
Protein Similarity: 60.8 60.9 N.A. 61.6 55.8 N.A.
P-Site Identity: 6.6 26.6 N.A. 13.3 13.3 N.A.
P-Site Similarity: 26.6 40 N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 12 6 0 0 0 12 0 12 6 34 34 0 12 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 17 6 6 0 0 0 6 0 0 6 6 0 0 % D
% Glu: 6 6 45 28 6 23 12 6 12 34 12 0 6 6 23 % E
% Phe: 0 6 0 0 0 0 0 0 0 0 6 6 0 12 0 % F
% Gly: 0 12 0 17 0 0 23 12 0 12 34 0 0 0 6 % G
% His: 0 0 0 0 0 0 6 0 0 0 12 0 0 12 0 % H
% Ile: 45 0 6 6 0 0 0 6 0 0 0 0 0 0 0 % I
% Lys: 6 0 12 6 56 17 12 6 6 12 0 12 6 6 6 % K
% Leu: 17 12 0 23 6 6 17 6 12 12 6 12 12 17 0 % L
% Met: 6 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 6 6 0 0 12 6 6 0 12 6 6 0 6 0 0 % N
% Pro: 0 0 6 0 0 0 6 6 6 0 0 6 6 0 34 % P
% Gln: 0 6 0 0 6 34 6 12 34 12 12 0 6 0 6 % Q
% Arg: 0 12 0 0 0 12 6 0 6 0 6 0 12 0 0 % R
% Ser: 6 23 6 6 6 0 0 12 0 6 0 12 12 6 6 % S
% Thr: 6 0 0 6 6 0 0 23 6 0 0 12 0 17 6 % T
% Val: 0 0 0 0 0 0 0 0 6 0 0 6 0 28 0 % V
% Trp: 0 17 0 0 0 0 0 6 0 0 0 0 0 0 6 % W
% Tyr: 0 0 0 0 0 6 0 0 0 0 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _