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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCS3
All Species:
50.3
Human Site:
Y223
Identified Species:
65.1
UniProt:
O95396
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95396
NP_055299.1
460
49669
Y223
H
Y
D
G
G
P
C
Y
R
C
I
F
P
Q
P
Chimpanzee
Pan troglodytes
XP_514724
460
49607
Y223
H
Y
D
G
G
P
C
Y
R
C
I
F
P
Q
P
Rhesus Macaque
Macaca mulatta
XP_001093903
462
49786
Y223
H
Y
D
G
G
P
C
Y
R
C
I
F
P
Q
P
Dog
Lupus familis
XP_543052
458
49108
Y221
H
Y
D
G
G
P
C
Y
R
C
V
F
P
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
A2BDX3
460
49356
Y223
H
H
D
G
G
P
C
Y
R
C
V
F
P
R
P
Rat
Rattus norvegicus
NP_001101274
458
49370
Y221
H
Y
D
D
G
P
C
Y
R
C
V
F
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508929
397
41903
S193
A
A
L
R
R
L
N
S
S
V
E
V
V
P
Y
Chicken
Gallus gallus
XP_001232656
468
50801
Y232
N
Y
H
G
G
P
C
Y
R
C
L
F
P
K
P
Frog
Xenopus laevis
Q58E95
451
49714
Y217
N
Y
H
Q
G
P
C
Y
R
C
L
F
P
K
P
Zebra Danio
Brachydanio rerio
Q8AWD2
459
50779
Y223
N
Y
R
G
G
P
C
Y
R
C
L
Y
P
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLJ8
453
50220
Y232
N
Y
A
N
G
P
C
Y
R
C
I
F
P
V
P
Honey Bee
Apis mellifera
XP_001120368
452
50498
R224
N
Y
N
G
P
C
Y
R
C
I
F
P
K
P
P
Nematode Worm
Caenorhab. elegans
O44510
402
44446
G198
S
V
T
N
C
N
E
G
G
V
L
G
P
I
V
Sea Urchin
Strong. purpuratus
XP_786162
380
41626
L176
I
R
Q
Y
D
M
V
L
D
C
T
D
N
V
A
Poplar Tree
Populus trichocarpa
XP_002300327
460
50018
Y227
N
H
N
R
G
P
C
Y
R
C
L
F
P
T
P
Maize
Zea mays
B6TNK6
468
50257
Y242
H
H
N
G
S
P
C
Y
R
C
L
F
P
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZNW0
464
50555
Y232
N
H
N
G
G
P
C
Y
R
C
L
F
P
T
P
Baker's Yeast
Sacchar. cerevisiae
P38820
440
49343
C208
N
F
N
N
I
G
P
C
Y
R
C
F
Y
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.1
91.5
N.A.
79.7
80.6
N.A.
52.8
64.3
58
60.8
N.A.
49.3
47.3
42.3
46
Protein Similarity:
100
99.7
96
95
N.A.
88
89.3
N.A.
62.8
77.9
73
77.8
N.A.
66.3
65.6
58
60.2
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
0
73.3
66.6
66.6
N.A.
73.3
20
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
93.3
86.6
86.6
N.A.
80
33.3
13.3
6.6
Percent
Protein Identity:
44.1
45.3
N.A.
41.8
36.7
N.A.
Protein Similarity:
60.8
60.9
N.A.
61.6
55.8
N.A.
P-Site Identity:
60
66.6
N.A.
66.6
6.6
N.A.
P-Site Similarity:
86.6
86.6
N.A.
93.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
0
0
0
0
0
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
6
6
73
6
6
78
6
0
0
0
0
% C
% Asp:
0
0
34
6
6
0
0
0
6
0
0
6
0
0
0
% D
% Glu:
0
0
0
0
0
0
6
0
0
0
6
0
0
0
0
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
6
73
0
0
0
% F
% Gly:
0
0
0
56
67
6
0
6
6
0
0
6
0
0
0
% G
% His:
39
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
0
6
0
0
0
0
6
23
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
6
12
0
% K
% Leu:
0
0
6
0
0
6
0
6
0
0
39
0
0
0
0
% L
% Met:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
45
0
28
17
0
6
6
0
0
0
0
0
6
0
0
% N
% Pro:
0
0
0
0
6
73
6
0
0
0
0
6
78
17
78
% P
% Gln:
0
0
6
6
0
0
0
0
0
0
0
0
0
23
0
% Q
% Arg:
0
6
6
12
6
0
0
6
73
6
0
0
0
12
0
% R
% Ser:
6
0
0
0
6
0
0
6
6
0
0
0
0
0
0
% S
% Thr:
0
0
6
0
0
0
0
0
0
0
6
0
0
17
6
% T
% Val:
0
6
0
0
0
0
6
0
0
12
17
6
6
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
56
0
6
0
0
6
73
6
0
0
6
6
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _