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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MOCS3
All Species:
38.79
Human Site:
Y341
Identified Species:
50.2
UniProt:
O95396
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95396
NP_055299.1
460
49669
Y341
E
R
V
S
V
T
D
Y
K
R
L
L
D
S
G
Chimpanzee
Pan troglodytes
XP_514724
460
49607
Y341
E
R
V
S
V
T
D
Y
K
R
L
L
D
S
G
Rhesus Macaque
Macaca mulatta
XP_001093903
462
49786
Y341
E
R
I
S
V
T
D
Y
K
R
V
L
D
S
G
Dog
Lupus familis
XP_543052
458
49108
Y339
E
R
V
S
V
A
D
Y
K
R
L
L
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
A2BDX3
460
49356
Y341
E
R
I
S
V
T
D
Y
K
R
L
L
D
S
G
Rat
Rattus norvegicus
NP_001101274
458
49370
Y339
E
R
I
S
V
T
D
Y
K
R
L
L
D
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508929
397
41903
K305
L
Q
A
L
E
V
L
K
I
A
A
G
L
E
P
Chicken
Gallus gallus
XP_001232656
468
50801
Y350
D
R
I
S
V
E
E
Y
K
K
L
L
D
E
Q
Frog
Xenopus laevis
Q58E95
451
49714
Y335
E
R
L
S
V
E
E
Y
K
R
L
L
D
D
H
Zebra Danio
Brachydanio rerio
Q8AWD2
459
50779
Y341
Q
R
V
S
V
Q
D
Y
K
G
I
L
D
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLJ8
453
50220
Y350
E
R
L
S
V
E
D
Y
Q
Q
K
I
Q
A
Q
Honey Bee
Apis mellifera
XP_001120368
452
50498
Y341
E
R
I
S
V
E
E
Y
N
I
M
K
L
D
T
Nematode Worm
Caenorhab. elegans
O44510
402
44446
D310
E
Q
K
P
V
L
L
D
T
R
P
S
L
E
F
Sea Urchin
Strong. purpuratus
XP_786162
380
41626
K288
D
G
T
Y
R
S
I
K
L
R
P
K
K
P
T
Poplar Tree
Populus trichocarpa
XP_002300327
460
50018
H345
L
P
E
D
H
R
I
H
S
R
E
L
K
E
R
Maize
Zea mays
B6TNK6
468
50257
I360
V
L
P
E
S
A
R
I
T
C
R
E
Y
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZNW0
464
50555
K350
A
E
S
R
I
S
S
K
E
F
K
E
I
L
Q
Baker's Yeast
Sacchar. cerevisiae
P38820
440
49343
F330
E
R
I
S
V
D
A
F
Q
R
I
Y
K
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.1
91.5
N.A.
79.7
80.6
N.A.
52.8
64.3
58
60.8
N.A.
49.3
47.3
42.3
46
Protein Similarity:
100
99.7
96
95
N.A.
88
89.3
N.A.
62.8
77.9
73
77.8
N.A.
66.3
65.6
58
60.2
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
0
53.3
66.6
60
N.A.
40
33.3
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
80
80
73.3
N.A.
73.3
53.3
26.6
20
Percent
Protein Identity:
44.1
45.3
N.A.
41.8
36.7
N.A.
Protein Similarity:
60.8
60.9
N.A.
61.6
55.8
N.A.
P-Site Identity:
13.3
0
N.A.
0
33.3
N.A.
P-Site Similarity:
20
0
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
12
6
0
0
6
6
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
12
0
0
6
0
6
45
6
0
0
0
0
50
17
6
% D
% Glu:
62
6
6
6
6
23
17
0
6
0
6
12
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
6
0
0
0
0
6
% F
% Gly:
0
6
0
0
0
0
0
0
0
6
0
6
0
0
34
% G
% His:
0
0
0
0
6
0
0
6
0
0
0
0
0
6
6
% H
% Ile:
0
0
34
0
6
0
12
6
6
6
12
6
6
0
0
% I
% Lys:
0
0
6
0
0
0
0
17
50
6
12
12
17
6
6
% K
% Leu:
12
6
12
6
0
6
12
0
6
0
39
56
17
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% N
% Pro:
0
6
6
6
0
0
0
0
0
0
12
0
0
6
6
% P
% Gln:
6
12
0
0
0
6
0
0
12
6
0
0
6
0
17
% Q
% Arg:
0
67
0
6
6
6
6
0
0
62
6
0
0
0
6
% R
% Ser:
0
0
6
67
6
12
6
0
6
0
0
6
0
34
6
% S
% Thr:
0
0
6
0
0
28
0
0
12
0
0
0
0
0
12
% T
% Val:
6
0
23
0
73
6
0
0
0
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
62
0
0
0
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _