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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS3 All Species: 53.64
Human Site: Y63 Identified Species: 69.41
UniProt: O95396 Number Species: 17
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95396 NP_055299.1 460 49669 Y63 S R D E I L R Y S R Q L V L P
Chimpanzee Pan troglodytes XP_514724 460 49607 Y63 S R D E I L R Y S R Q L V L P
Rhesus Macaque Macaca mulatta XP_001093903 462 49786 Y63 S P D E I L R Y S R Q L V L P
Dog Lupus familis XP_543052 458 49108 Y61 S R E E I L R Y S R Q L V L P
Cat Felis silvestris
Mouse Mus musculus A2BDX3 460 49356 Y63 S R D E I L R Y S R Q L L L P
Rat Rattus norvegicus NP_001101274 458 49370 Y61 S R D E I L R Y S R Q L L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508929 397 41903 C44 W E G G I L R C G P P P S S G
Chicken Gallus gallus XP_001232656 468 50801 Y72 S P A D I L R Y S R Q L V L P
Frog Xenopus laevis Q58E95 451 49714 Y57 T N P D I L R Y S R Q L V L P
Zebra Danio Brachydanio rerio Q8AWD2 459 50779 Y63 N N D D I M R Y S R Q L L L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLJ8 453 50220 Y72 T N D D I A R Y S R Q L I L P
Honey Bee Apis mellifera XP_001120368 452 50498 Y64 N N E E I L R Y S R Q I F L P
Nematode Worm Caenorhab. elegans O44510 402 44446 G49 I V G A G G L G C P V A T Y L
Sea Urchin Strong. purpuratus XP_786162 380 41626 E27 R L Q L E K H E L E L M K A E
Poplar Tree Populus trichocarpa XP_002300327 460 50018 Y67 S P D M I Y R Y S R Q L L L P
Maize Zea mays B6TNK6 468 50257 Y82 P A D M I Y R Y S R H L L L P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZNW0 464 50555 Y72 S P D Q I Y R Y S R Q L L L P
Baker's Yeast Sacchar. cerevisiae P38820 440 49343 T56 R Q M I V E E T G G V A G Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.1 91.5 N.A. 79.7 80.6 N.A. 52.8 64.3 58 60.8 N.A. 49.3 47.3 42.3 46
Protein Similarity: 100 99.7 96 95 N.A. 88 89.3 N.A. 62.8 77.9 73 77.8 N.A. 66.3 65.6 58 60.2
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 20 80 73.3 66.6 N.A. 66.6 66.6 0 0
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 20 86.6 86.6 93.3 N.A. 86.6 86.6 0 6.6
Percent
Protein Identity: 44.1 45.3 N.A. 41.8 36.7 N.A.
Protein Similarity: 60.8 60.9 N.A. 61.6 55.8 N.A.
P-Site Identity: 73.3 60 N.A. 73.3 0 N.A.
P-Site Similarity: 80 66.6 N.A. 86.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 6 6 0 6 0 0 0 0 0 12 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 6 6 0 0 0 0 0 0 % C
% Asp: 0 0 56 23 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 6 12 39 6 6 6 6 0 6 0 0 0 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 0 0 12 6 6 6 0 6 12 6 0 0 6 0 6 % G
% His: 0 0 0 0 0 0 6 0 0 0 6 0 0 0 0 % H
% Ile: 6 0 0 6 84 0 0 0 0 0 0 6 6 0 0 % I
% Lys: 0 0 0 0 0 6 0 0 0 0 0 0 6 0 0 % K
% Leu: 0 6 0 6 0 56 6 0 6 0 6 73 34 78 6 % L
% Met: 0 0 6 12 0 6 0 0 0 0 0 6 0 0 0 % M
% Asn: 12 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 6 23 6 0 0 0 0 0 0 12 6 6 0 0 78 % P
% Gln: 0 6 6 6 0 0 0 0 0 0 73 0 0 6 0 % Q
% Arg: 12 28 0 0 0 0 84 0 0 78 0 0 0 0 0 % R
% Ser: 50 0 0 0 0 0 0 0 78 0 0 0 6 6 0 % S
% Thr: 12 0 0 0 0 0 0 6 0 0 0 0 6 0 0 % T
% Val: 0 6 0 0 6 0 0 0 0 0 12 0 34 0 6 % V
% Trp: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 78 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _