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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
17.58
Human Site:
S1327
Identified Species:
32.22
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S1327
D
D
Q
H
N
C
L
S
D
P
A
D
H
S
R
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
S1327
D
D
Q
H
N
C
L
S
D
P
A
D
H
S
R
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
S1446
E
Q
D
L
S
I
L
S
T
C
Y
Q
F
A
K
Dog
Lupus familis
XP_532576
1423
156113
S1325
D
D
Q
H
S
C
L
S
D
P
A
D
H
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
S1433
D
Q
D
I
S
I
L
S
S
S
Y
Q
F
A
K
Rat
Rattus norvegicus
NP_001101422
1398
152379
S1300
D
D
H
R
T
C
L
S
D
P
A
D
H
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
A1430
D
Q
D
L
S
T
S
A
A
H
Y
Q
F
A
K
Chicken
Gallus gallus
XP_422473
1328
145070
V1239
N
A
V
M
M
G
M
V
F
V
V
S
P
I
D
Frog
Xenopus laevis
NP_001079166
1235
135066
E1147
A
D
H
S
R
L
T
E
N
V
A
K
A
F
C
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
E1121
A
D
H
S
R
L
A
E
N
V
A
R
A
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
T1245
K
C
E
D
W
Y
A
T
N
G
G
N
C
E
E
Honey Bee
Apis mellifera
XP_396901
1227
137615
L1139
D
P
V
D
I
N
K
L
S
G
N
I
A
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
L1500
G
L
G
E
G
E
S
L
G
H
P
N
V
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
13.3
93.3
N.A.
20
80
N.A.
6.6
0
13.3
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
40
100
N.A.
40
80
N.A.
33.3
13.3
20
20
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
16
8
8
0
47
0
24
24
8
% A
% Cys:
0
8
0
0
0
31
0
0
0
8
0
0
8
0
16
% C
% Asp:
54
47
24
16
0
0
0
0
31
0
0
31
0
0
8
% D
% Glu:
8
0
8
8
0
8
0
16
0
0
0
0
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
24
16
0
% F
% Gly:
8
0
8
0
8
8
0
0
8
16
8
0
0
0
0
% G
% His:
0
0
24
24
0
0
0
0
0
16
0
0
31
0
0
% H
% Ile:
0
0
0
8
8
16
0
0
0
0
0
8
0
8
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
8
0
8
24
% K
% Leu:
0
8
0
16
0
16
47
16
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
16
8
0
0
24
0
8
16
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
31
8
0
8
8
0
% P
% Gln:
0
24
24
0
0
0
0
0
0
0
0
24
0
0
0
% Q
% Arg:
0
0
0
8
16
0
0
0
0
0
0
8
0
0
31
% R
% Ser:
0
0
0
16
31
0
16
47
16
8
0
8
0
31
0
% S
% Thr:
0
0
0
0
8
8
8
8
8
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
8
0
24
8
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _