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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
13.33
Human Site:
S182
Identified Species:
24.44
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S182
Q
S
L
M
D
A
F
S
C
S
L
D
N
E
N
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
S182
Q
S
L
M
D
A
F
S
C
S
L
D
N
E
N
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
I201
S
E
L
Q
N
R
E
I
G
G
I
K
E
L
G
Dog
Lupus familis
XP_532576
1423
156113
S182
Q
S
L
V
D
A
F
S
C
S
L
D
N
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
G204
D
I
S
I
K
E
L
G
V
K
V
D
M
A
L
Rat
Rattus norvegicus
NP_001101422
1398
152379
D158
V
A
V
M
H
N
C
D
K
R
T
L
Q
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
L197
P
L
Q
N
I
E
H
L
A
A
R
K
L
D
F
Chicken
Gallus gallus
XP_422473
1328
145070
T161
M
H
N
C
D
R
R
T
L
Q
S
G
D
L
L
Frog
Xenopus laevis
NP_001079166
1235
135066
D72
P
K
S
I
I
N
F
D
C
L
T
M
D
N
E
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
L46
I
L
A
P
P
S
H
L
L
S
L
N
P
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
S156
P
S
P
V
S
N
G
S
H
S
E
E
L
A
T
Honey Bee
Apis mellifera
XP_396901
1227
137615
T64
T
D
V
N
Q
F
Y
T
Q
E
C
T
N
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
D252
K
Q
S
L
E
E
R
D
S
L
E
S
S
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
6.6
N.A.
0
6.6
13.3
13.3
N.A.
20
13.3
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
20
26.6
N.A.
13.3
20
26.6
26.6
N.A.
33.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
24
0
0
8
8
0
0
0
24
0
% A
% Cys:
0
0
0
8
0
0
8
0
31
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
31
0
0
24
0
0
0
31
16
16
8
% D
% Glu:
0
8
0
0
8
24
8
0
0
8
16
8
8
24
8
% E
% Phe:
0
0
0
0
0
8
31
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
8
8
8
0
8
0
8
8
% G
% His:
0
8
0
0
8
0
16
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
16
16
0
0
8
0
0
8
0
0
0
8
% I
% Lys:
8
8
0
0
8
0
0
0
8
8
0
16
0
0
0
% K
% Leu:
0
16
31
8
0
0
8
16
16
16
31
8
16
16
24
% L
% Met:
8
0
0
24
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
8
16
8
24
0
0
0
0
0
8
31
8
31
% N
% Pro:
24
0
8
8
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
24
8
8
8
8
0
0
0
8
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
16
16
0
0
8
8
0
0
0
0
% R
% Ser:
8
31
24
0
8
8
0
31
8
39
8
8
8
8
0
% S
% Thr:
8
0
0
0
0
0
0
16
0
0
16
8
0
0
8
% T
% Val:
8
0
16
16
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _