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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
12.12
Human Site:
S257
Identified Species:
22.22
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S257
G
S
I
G
R
D
P
S
M
S
A
I
T
S
L
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
S257
G
S
I
G
R
D
P
S
M
S
A
I
T
S
L
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
L276
E
L
L
K
D
D
G
L
V
K
E
E
V
G
V
Dog
Lupus familis
XP_532576
1423
156113
S257
E
T
T
G
R
D
P
S
M
S
V
I
T
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
A279
C
L
A
E
E
K
V
A
V
A
V
N
N
T
E
Rat
Rattus norvegicus
NP_001101422
1398
152379
S233
L
N
H
L
C
A
A
S
A
N
S
A
T
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
G272
C
E
L
L
K
D
N
G
C
L
R
Q
E
V
H
Chicken
Gallus gallus
XP_422473
1328
145070
T236
N
A
S
S
E
T
L
T
V
A
C
P
S
S
C
Frog
Xenopus laevis
NP_001079166
1235
135066
A147
I
K
P
Y
S
T
C
A
A
L
S
F
E
N
N
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
L121
P
Q
P
N
I
G
K
L
V
S
T
D
G
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
L231
G
T
E
S
Q
S
L
L
P
E
E
V
T
A
S
Honey Bee
Apis mellifera
XP_396901
1227
137615
N139
S
N
V
F
S
S
L
N
E
Y
I
N
A
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
K327
T
P
E
Q
S
P
L
K
N
T
S
D
K
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
6.6
73.3
N.A.
0
20
N.A.
6.6
6.6
0
13.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
26.6
80
N.A.
26.6
46.6
N.A.
20
40
20
20
N.A.
40
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
8
16
16
16
16
8
8
8
0
% A
% Cys:
16
0
0
0
8
0
8
0
8
0
8
0
0
0
8
% C
% Asp:
0
0
0
0
8
39
0
0
0
0
0
16
0
8
0
% D
% Glu:
16
8
16
8
16
0
0
0
8
8
16
8
16
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
24
0
0
24
0
8
8
8
0
0
0
0
8
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
16
0
8
0
0
0
0
0
8
24
0
0
8
% I
% Lys:
0
8
0
8
8
8
8
8
0
8
0
0
8
0
0
% K
% Leu:
8
16
16
16
0
0
31
24
0
16
0
0
0
0
31
% L
% Met:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% M
% Asn:
8
16
0
8
0
0
8
8
8
8
0
16
8
8
8
% N
% Pro:
8
8
16
0
0
8
24
0
8
0
0
8
0
8
8
% P
% Gln:
0
8
0
8
8
0
0
0
0
0
0
8
0
8
8
% Q
% Arg:
0
0
0
0
24
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
16
8
16
24
16
0
31
0
31
24
0
8
39
8
% S
% Thr:
8
16
8
0
0
16
0
8
0
8
8
0
39
8
0
% T
% Val:
0
0
8
0
0
0
8
0
31
0
16
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _