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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
10
Human Site:
S299
Identified Species:
18.33
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S299
D
L
T
G
K
I
S
S
P
R
T
D
L
G
S
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
S299
D
L
T
G
K
I
S
S
P
R
T
D
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
S318
L
C
L
N
D
L
N
S
R
D
E
N
F
K
L
Dog
Lupus familis
XP_532576
1423
156113
S299
V
L
T
G
K
T
G
S
A
R
T
D
L
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
F321
P
A
S
K
D
E
N
F
K
L
P
D
F
P
L
Rat
Rattus norvegicus
NP_001101422
1398
152379
G275
T
S
Q
G
M
D
G
G
P
A
I
K
K
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
R314
Y
P
P
D
R
N
I
R
L
P
D
C
F
L
S
Chicken
Gallus gallus
XP_422473
1328
145070
V278
K
R
P
V
D
G
I
V
K
M
Q
E
N
C
L
Frog
Xenopus laevis
NP_001079166
1235
135066
H189
Q
K
H
T
S
S
L
H
E
E
K
L
F
E
G
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
T163
I
R
F
N
D
D
E
T
N
Q
P
V
I
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
L273
I
D
V
P
L
A
N
L
P
A
S
V
A
E
V
Honey Bee
Apis mellifera
XP_396901
1227
137615
Q181
N
E
I
P
N
L
I
Q
I
N
T
K
D
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
D369
T
V
S
Q
S
E
L
D
E
L
E
D
L
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
6.6
73.3
N.A.
6.6
13.3
N.A.
6.6
0
0
0
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
100
26.6
73.3
N.A.
20
13.3
N.A.
13.3
6.6
0
20
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
8
16
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
16
8
0
8
31
16
0
8
0
8
8
39
8
16
8
% D
% Glu:
0
8
0
0
0
16
8
0
16
8
16
8
0
16
8
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
31
0
0
% F
% Gly:
0
0
0
31
0
8
16
8
0
0
0
0
0
24
8
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
16
0
8
0
0
16
24
0
8
0
8
0
8
0
0
% I
% Lys:
8
8
0
8
24
0
0
0
16
0
8
16
8
8
8
% K
% Leu:
8
24
8
0
8
16
16
8
8
16
0
8
31
8
24
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
0
16
8
8
24
0
8
8
0
8
8
8
0
% N
% Pro:
8
8
16
16
0
0
0
0
31
8
16
0
0
8
0
% P
% Gln:
8
0
8
8
0
0
0
8
0
8
8
0
0
8
0
% Q
% Arg:
0
16
0
0
8
0
0
8
8
24
0
0
0
0
0
% R
% Ser:
0
8
16
0
16
8
16
31
0
0
8
0
0
0
39
% S
% Thr:
16
0
24
8
0
8
0
8
0
0
31
0
0
0
0
% T
% Val:
8
8
8
8
0
0
0
8
0
0
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _