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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
8.79
Human Site:
S463
Identified Species:
16.11
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S463
E
S
E
E
C
D
F
S
T
V
I
D
T
P
A
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
A463
E
S
E
E
C
E
F
A
T
V
I
D
T
P
A
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
S494
G
T
N
V
L
E
S
S
D
C
C
E
G
F
I
Dog
Lupus familis
XP_532576
1423
156113
D461
M
N
E
S
E
G
S
D
F
S
T
M
D
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
S494
C
E
G
L
T
F
P
S
S
D
M
D
G
Q
E
Rat
Rattus norvegicus
NP_001101422
1398
152379
S437
E
S
E
G
Y
D
F
S
T
V
S
D
A
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
S487
L
S
S
K
D
I
I
S
Q
V
L
E
D
F
N
Chicken
Gallus gallus
XP_422473
1328
145070
G440
E
S
G
I
D
L
K
G
T
G
T
D
E
L
E
Frog
Xenopus laevis
NP_001079166
1235
135066
T350
Q
Q
R
E
D
D
V
T
E
R
G
G
L
L
L
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
D324
L
S
D
G
L
V
E
D
L
D
G
D
A
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
H435
E
V
E
V
D
R
E
H
E
D
A
S
L
A
T
Honey Bee
Apis mellifera
XP_396901
1227
137615
H342
L
R
E
S
Y
N
K
H
E
N
I
I
T
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
D572
Q
T
N
Q
Q
L
P
D
S
T
G
G
H
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
86.6
6.6
6.6
N.A.
13.3
73.3
N.A.
20
26.6
13.3
13.3
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
100
26.6
13.3
N.A.
26.6
73.3
N.A.
40
26.6
26.6
20
N.A.
13.3
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
16
8
24
% A
% Cys:
8
0
0
0
16
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
0
8
0
31
24
0
24
8
24
0
47
16
0
0
% D
% Glu:
39
8
47
24
8
16
16
0
24
0
0
16
8
0
16
% E
% Phe:
0
0
0
0
0
8
24
0
8
0
0
0
0
16
0
% F
% Gly:
8
0
16
16
0
8
0
8
0
8
24
16
16
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
8
8
0
0
0
24
8
0
0
8
% I
% Lys:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% K
% Leu:
24
0
0
8
16
16
0
0
8
0
8
0
16
16
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
8
16
0
0
8
0
0
0
8
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
16
0
0
0
0
0
0
31
8
% P
% Gln:
16
8
0
8
8
0
0
0
8
0
0
0
0
16
0
% Q
% Arg:
0
8
8
0
0
8
0
0
0
8
0
0
0
8
0
% R
% Ser:
0
47
8
16
0
0
16
39
16
8
8
8
0
0
8
% S
% Thr:
0
16
0
0
8
0
0
8
31
8
16
0
24
8
16
% T
% Val:
0
8
0
16
0
8
8
0
0
31
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _