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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
11.52
Human Site:
S596
Identified Species:
21.11
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
S596
L
Q
I
P
K
P
L
S
D
H
L
Q
N
D
F
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
S596
L
Q
I
P
K
P
L
S
D
H
L
Q
N
D
F
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
S627
I
E
Q
G
L
L
T
S
K
S
E
I
T
N
E
Dog
Lupus familis
XP_532576
1423
156113
S594
L
Q
I
P
K
P
L
S
D
H
L
Q
N
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
I627
D
E
L
P
V
P
S
I
K
T
Q
A
V
G
G
Rat
Rattus norvegicus
NP_001101422
1398
152379
D570
Q
I
P
K
P
L
S
D
H
L
Q
N
D
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
A620
I
N
G
Q
T
I
H
A
G
G
A
R
P
K
Q
Chicken
Gallus gallus
XP_422473
1328
145070
P573
G
G
A
R
P
K
Q
P
T
N
L
K
L
Q
I
Frog
Xenopus laevis
NP_001079166
1235
135066
L483
R
G
P
G
S
L
C
L
A
V
S
P
D
S
P
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
E457
S
G
L
I
I
P
S
E
S
P
D
N
D
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
R568
C
S
V
C
C
S
Q
R
F
R
L
E
F
A
T
Honey Bee
Apis mellifera
XP_396901
1227
137615
S475
S
P
D
I
V
E
N
S
V
P
E
S
G
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
S705
T
A
Q
P
V
P
P
S
M
S
P
E
M
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
6.6
93.3
N.A.
13.3
0
N.A.
0
6.6
0
6.6
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
100
26.6
93.3
N.A.
26.6
6.6
N.A.
20
20
6.6
20
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
8
0
8
8
0
8
0
% A
% Cys:
8
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
8
24
0
8
0
24
24
0
% D
% Glu:
0
16
0
0
0
8
0
8
0
0
16
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
16
% F
% Gly:
8
24
8
16
0
0
0
0
8
8
0
0
8
16
8
% G
% His:
0
0
0
0
0
0
8
0
8
24
0
0
0
0
0
% H
% Ile:
16
8
24
16
8
8
0
8
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
24
8
0
0
16
0
0
8
0
8
0
% K
% Leu:
24
0
16
0
8
24
24
8
0
8
39
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
8
0
16
24
8
0
% N
% Pro:
0
8
16
39
16
47
8
8
0
16
8
8
8
8
16
% P
% Gln:
8
24
16
8
0
0
16
0
0
0
16
24
0
8
16
% Q
% Arg:
8
0
0
8
0
0
0
8
0
8
0
8
0
0
0
% R
% Ser:
16
8
0
0
8
8
24
47
8
16
8
8
0
8
0
% S
% Thr:
8
0
0
0
8
0
8
0
8
8
0
0
8
0
8
% T
% Val:
0
0
8
0
24
0
0
0
8
8
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _