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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
18.48
Human Site:
T1292
Identified Species:
33.89
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
T1292
G
K
S
M
E
T
I
T
N
V
K
I
F
H
G
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
T1292
G
K
S
M
E
T
I
T
N
V
K
I
F
H
G
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
P1411
G
M
S
L
Q
G
F
P
S
E
K
I
K
L
E
Dog
Lupus familis
XP_532576
1423
156113
T1290
G
K
S
M
E
S
I
T
S
V
K
I
F
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
P1398
G
M
S
V
E
G
F
P
S
E
K
I
K
L
E
Rat
Rattus norvegicus
NP_001101422
1398
152379
T1265
G
K
S
M
E
S
I
T
N
V
K
I
F
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
P1395
G
K
S
L
E
G
I
P
S
E
R
I
Y
Q
E
Chicken
Gallus gallus
XP_422473
1328
145070
S1204
S
G
A
L
K
S
S
S
G
Y
L
A
K
S
S
Frog
Xenopus laevis
NP_001079166
1235
135066
Y1112
K
I
F
H
G
S
E
Y
K
A
S
G
K
I
I
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
Y1086
K
I
F
H
G
S
E
Y
K
A
N
G
K
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
S1210
D
Q
P
M
D
G
I
S
N
M
R
V
L
K
W
Honey Bee
Apis mellifera
XP_396901
1227
137615
I1104
S
I
R
V
H
N
G
I
D
Y
K
G
T
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
E1465
G
Q
S
L
T
G
V
E
S
V
R
I
H
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
26.6
86.6
N.A.
33.3
93.3
N.A.
40
0
0
0
N.A.
20
6.6
N.A.
33.3
P-Site Similarity:
100
100
46.6
100
N.A.
46.6
100
N.A.
66.6
33.3
6.6
6.6
N.A.
60
20
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
16
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
47
0
16
8
0
24
0
0
0
0
24
% E
% Phe:
0
0
16
0
0
0
16
0
0
0
0
0
31
0
0
% F
% Gly:
62
8
0
0
16
39
8
0
8
0
0
24
0
0
39
% G
% His:
0
0
0
16
8
0
0
0
0
0
0
0
8
31
0
% H
% Ile:
0
24
0
0
0
0
47
8
0
0
0
62
0
8
16
% I
% Lys:
16
39
0
0
8
0
0
0
16
0
54
0
39
8
0
% K
% Leu:
0
0
0
31
0
0
0
0
0
0
8
0
8
16
0
% L
% Met:
0
16
0
39
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
31
0
8
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
24
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
24
0
0
0
8
% R
% Ser:
16
0
62
0
0
39
8
16
39
0
8
0
0
16
8
% S
% Thr:
0
0
0
0
8
16
0
31
0
0
0
0
8
0
0
% T
% Val:
0
0
0
16
0
0
8
0
0
39
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
16
0
16
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _