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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
6.06
Human Site:
T221
Identified Species:
11.11
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
T221
D
P
L
N
R
P
K
T
E
G
R
S
V
N
H
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
T221
D
P
L
N
R
P
K
T
E
G
R
S
V
N
H
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
D240
N
H
L
E
P
I
V
D
F
N
M
S
S
A
L
Dog
Lupus familis
XP_532576
1423
156113
A221
D
L
L
N
R
P
S
A
V
G
D
S
V
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
L243
D
F
D
M
P
S
V
L
M
E
Q
S
S
E
M
Rat
Rattus norvegicus
NP_001101422
1398
152379
F197
R
Q
T
D
Q
F
S
F
S
M
N
G
S
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
Q236
N
K
I
H
N
L
E
Q
I
A
G
L
N
S
A
Chicken
Gallus gallus
XP_422473
1328
145070
V200
S
D
E
F
S
V
T
V
N
G
S
M
E
K
D
Frog
Xenopus laevis
NP_001079166
1235
135066
V111
I
I
Q
D
T
S
N
V
S
T
D
P
A
I
N
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
T85
G
P
S
L
V
E
V
T
R
L
N
G
K
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
D195
K
H
E
D
Q
H
Q
D
Q
A
V
P
P
P
T
Honey Bee
Apis mellifera
XP_396901
1227
137615
Q103
S
Q
K
T
S
I
I
Q
K
Q
Q
N
S
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
S291
G
S
P
S
S
Y
T
S
S
S
S
T
P
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
13.3
60
N.A.
13.3
0
N.A.
0
6.6
0
13.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
20
60
N.A.
20
13.3
N.A.
33.3
6.6
13.3
13.3
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
16
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
8
8
24
0
0
0
16
0
0
16
0
0
0
8
% D
% Glu:
0
0
16
8
0
8
8
0
16
8
0
0
8
8
8
% E
% Phe:
0
8
0
8
0
8
0
8
8
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
0
0
0
0
31
8
16
0
0
8
% G
% His:
0
16
0
8
0
8
0
0
0
0
0
0
0
0
24
% H
% Ile:
8
8
8
0
0
16
8
0
8
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
0
0
16
0
8
0
0
0
8
16
0
% K
% Leu:
0
8
31
8
0
8
0
8
0
8
0
8
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
8
8
8
8
0
0
8
% M
% Asn:
16
0
0
24
8
0
8
0
8
8
16
8
8
16
8
% N
% Pro:
0
24
8
0
16
24
0
0
0
0
0
16
16
16
0
% P
% Gln:
0
16
8
0
16
0
8
16
8
8
16
0
0
8
0
% Q
% Arg:
8
0
0
0
24
0
0
0
8
0
16
0
0
0
0
% R
% Ser:
16
8
8
8
24
16
16
8
24
8
16
39
31
16
8
% S
% Thr:
0
0
8
8
8
0
16
24
0
8
0
8
0
0
8
% T
% Val:
0
0
0
0
8
8
24
16
8
0
8
0
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _