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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
6.67
Human Site:
T431
Identified Species:
12.22
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
T431
Q
I
S
Q
P
E
D
T
N
G
D
S
G
G
Q
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
T431
Q
I
S
Q
P
E
D
T
N
G
D
S
G
G
Q
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
E450
I
V
L
Q
P
L
I
E
G
M
E
D
R
K
I
Dog
Lupus familis
XP_532576
1423
156113
I431
P
M
N
Q
P
E
D
I
Y
N
D
S
G
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
P460
S
G
E
S
L
E
S
P
E
D
A
S
S
A
A
Rat
Rattus norvegicus
NP_001101422
1398
152379
P407
Q
I
S
Q
P
E
D
P
Q
S
A
G
E
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
T452
T
E
F
S
P
C
H
T
N
L
P
V
A
A
D
Chicken
Gallus gallus
XP_422473
1328
145070
E409
K
Q
T
V
E
E
N
E
R
L
L
Q
T
K
Q
Frog
Xenopus laevis
NP_001079166
1235
135066
E320
P
K
N
L
P
S
K
E
D
S
V
T
E
E
K
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
E294
N
S
A
S
N
Q
E
E
K
E
K
M
L
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
M404
E
S
T
P
V
T
A
M
G
E
D
V
A
S
S
Honey Bee
Apis mellifera
XP_396901
1227
137615
S312
T
H
K
S
I
G
F
S
N
I
D
D
L
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
F536
E
L
A
N
V
D
P
F
Y
G
G
K
P
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
13.3
53.3
N.A.
13.3
46.6
N.A.
20
13.3
6.6
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
26.6
73.3
N.A.
13.3
46.6
N.A.
20
33.3
33.3
20
N.A.
20
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
8
0
0
0
16
0
16
16
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
31
0
8
8
39
16
0
0
8
% D
% Glu:
16
8
8
0
8
47
8
31
8
16
8
0
16
8
16
% E
% Phe:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
8
0
0
16
24
8
8
24
24
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
24
0
0
8
0
8
8
0
8
0
0
0
0
8
% I
% Lys:
8
8
8
0
0
0
8
0
8
0
8
8
0
24
8
% K
% Leu:
0
8
8
8
8
8
0
0
0
16
8
0
16
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% M
% Asn:
8
0
16
8
8
0
8
0
31
8
0
0
0
0
0
% N
% Pro:
16
0
0
8
54
0
8
16
0
0
8
0
8
0
0
% P
% Gln:
24
8
0
39
0
8
0
0
8
0
0
8
0
8
24
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% R
% Ser:
8
16
24
31
0
8
8
8
0
16
0
31
8
16
8
% S
% Thr:
16
0
16
0
0
8
0
24
0
0
0
8
8
0
8
% T
% Val:
0
8
0
8
16
0
0
0
0
0
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _