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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFYVE9 All Species: 14.55
Human Site: T538 Identified Species: 26.67
UniProt: O95405 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95405 NP_004790.2 1425 156403 T538 S G L L L N S T G D L M K K N
Chimpanzee Pan troglodytes XP_513406 1425 156248 T538 S G L L L N S T G D L M K K N
Rhesus Macaque Macaca mulatta XP_001110183 1540 169100 D569 M N H I D M K D L D D G N I N
Dog Lupus familis XP_532576 1423 156113 T536 S G L L L N S T G D L M K K N
Cat Felis silvestris
Mouse Mus musculus Q80U44 1528 166652 N569 N A G D I Y F N A E A G A A G
Rat Rattus norvegicus NP_001101422 1398 152379 T512 N G L L L N S T G T I M K K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510291 1525 166161 T562 L R S E D E E T C D I T R S G
Chicken Gallus gallus XP_422473 1328 145070 E515 V Y E Q R G N E T I E G S G L
Frog Xenopus laevis NP_001079166 1235 135066 I425 E M L Q S D L I P P N A G C S
Zebra Danio Brachydanio rerio XP_001344504 1209 132102 Q399 N L K L Q I P Q P L S N Q V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524729 1343 146291 E510 D E E S P I Y E A V G Y S D P
Honey Bee Apis mellifera XP_396901 1227 137615 N417 K P N I S D I N N E S E K P I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781105 1601 173741 E647 D L A P G D K E H Q R Q R N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 33.5 90.3 N.A. 33.9 85.2 N.A. 35.5 70 59 56.6 N.A. 25.8 34 N.A. 31.6
Protein Similarity: 100 99.6 50.9 94.6 N.A. 51.3 90.1 N.A. 51.7 78.1 69.8 69.1 N.A. 44.1 53.2 N.A. 51.4
P-Site Identity: 100 100 13.3 100 N.A. 0 80 N.A. 13.3 0 6.6 6.6 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 20 100 N.A. 20 93.3 N.A. 26.6 6.6 20 20 N.A. 0 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 0 16 0 8 8 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % C
% Asp: 16 0 0 8 16 24 0 8 0 39 8 0 0 8 0 % D
% Glu: 8 8 16 8 0 8 8 24 0 16 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 31 8 0 8 8 0 0 31 0 8 24 8 8 16 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 8 16 8 8 0 8 16 0 0 8 8 % I
% Lys: 8 0 8 0 0 0 16 0 0 0 0 0 39 31 0 % K
% Leu: 8 16 39 39 31 0 8 0 8 8 24 0 0 0 8 % L
% Met: 8 8 0 0 0 8 0 0 0 0 0 31 0 0 0 % M
% Asn: 24 8 8 0 0 31 8 16 8 0 8 8 8 8 39 % N
% Pro: 0 8 0 8 8 0 8 0 16 8 0 0 0 8 8 % P
% Gln: 0 0 0 16 8 0 0 8 0 8 0 8 8 0 8 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 8 0 16 0 0 % R
% Ser: 24 0 8 8 16 0 31 0 0 0 16 0 16 8 8 % S
% Thr: 0 0 0 0 0 0 0 39 8 8 0 8 0 0 8 % T
% Val: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _