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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
12.73
Human Site:
T868
Identified Species:
23.33
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
T868
H
D
P
V
K
P
V
T
T
S
P
L
P
A
E
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
T868
H
D
P
V
K
P
V
T
T
S
P
L
P
A
E
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
P941
R
N
E
I
I
Q
S
P
I
S
Q
V
P
S
V
Dog
Lupus familis
XP_532576
1423
156113
T866
H
D
P
V
K
P
I
T
T
S
P
L
P
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
T968
V
D
S
E
E
P
S
T
P
T
V
V
P
A
N
Rat
Rattus norvegicus
NP_001101422
1398
152379
A841
H
D
P
V
K
P
V
A
T
S
P
L
P
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
I892
L
P
D
L
P
T
N
I
S
P
V
D
H
I
P
Chicken
Gallus gallus
XP_422473
1328
145070
R817
A
Q
P
R
E
Q
R
R
V
W
F
A
D
G
I
Frog
Xenopus laevis
NP_001079166
1235
135066
G725
L
I
S
T
G
V
K
G
D
Y
A
V
E
E
R
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
G699
L
I
S
T
G
V
K
G
D
Y
A
V
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
S811
G
L
P
P
I
C
I
S
S
K
E
G
G
E
V
Honey Bee
Apis mellifera
XP_396901
1227
137615
H717
H
K
G
Q
V
S
Y
H
A
V
T
N
E
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
A1035
P
T
T
G
D
S
S
A
Q
N
I
P
T
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
100
13.3
93.3
N.A.
33.3
93.3
N.A.
0
6.6
0
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
40
100
N.A.
53.3
93.3
N.A.
13.3
13.3
6.6
6.6
N.A.
26.6
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
16
8
0
16
8
0
39
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
8
0
8
0
0
0
16
0
0
8
8
0
0
% D
% Glu:
0
0
8
8
16
0
0
0
0
0
8
0
24
24
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
8
8
16
0
0
16
0
0
0
8
8
8
0
% G
% His:
39
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
16
0
8
16
0
16
8
8
0
8
0
0
8
16
% I
% Lys:
0
8
0
0
31
0
16
0
0
8
0
0
0
0
0
% K
% Leu:
24
8
0
8
0
0
0
0
0
0
0
31
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
8
0
8
0
8
8
% N
% Pro:
8
8
47
8
8
39
0
8
8
8
31
8
47
0
8
% P
% Gln:
0
8
0
8
0
16
0
0
8
0
8
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
8
8
0
0
0
0
0
0
16
% R
% Ser:
0
0
24
0
0
16
24
8
16
39
0
0
0
16
0
% S
% Thr:
0
8
8
16
0
8
0
31
31
8
8
0
8
0
0
% T
% Val:
8
0
0
31
8
16
24
0
8
8
16
31
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _