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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE9
All Species:
14.24
Human Site:
Y546
Identified Species:
26.11
UniProt:
O95405
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95405
NP_004790.2
1425
156403
Y546
G
D
L
M
K
K
N
Y
L
H
N
F
C
S
Q
Chimpanzee
Pan troglodytes
XP_513406
1425
156248
Y546
G
D
L
M
K
K
N
Y
L
R
N
F
C
S
Q
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
N577
L
D
D
G
N
I
N
N
I
Y
F
N
A
E
A
Dog
Lupus familis
XP_532576
1423
156113
Y544
G
D
L
M
K
K
N
Y
L
H
S
F
C
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
E577
A
E
A
G
A
A
G
E
N
G
G
V
G
N
C
Rat
Rattus norvegicus
NP_001101422
1398
152379
Y520
G
T
I
M
K
K
N
Y
L
H
N
F
C
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
E570
C
D
I
T
R
S
G
E
T
I
D
A
Q
G
E
Chicken
Gallus gallus
XP_422473
1328
145070
I523
T
I
E
G
S
G
L
I
L
N
S
A
G
D
Q
Frog
Xenopus laevis
NP_001079166
1235
135066
S433
P
P
N
A
G
C
S
S
K
Y
K
N
D
M
L
Zebra Danio
Brachydanio rerio
XP_001344504
1209
132102
N407
P
L
S
N
Q
V
Q
N
E
F
G
T
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524729
1343
146291
H518
A
V
G
Y
S
D
P
H
A
N
L
G
K
V
P
Honey Bee
Apis mellifera
XP_396901
1227
137615
R425
N
E
S
E
K
P
I
R
P
Q
T
L
D
I
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
S655
H
Q
R
Q
R
N
T
S
H
Q
S
S
P
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
33.5
90.3
N.A.
33.9
85.2
N.A.
35.5
70
59
56.6
N.A.
25.8
34
N.A.
31.6
Protein Similarity:
100
99.6
50.9
94.6
N.A.
51.3
90.1
N.A.
51.7
78.1
69.8
69.1
N.A.
44.1
53.2
N.A.
51.4
P-Site Identity:
100
93.3
13.3
93.3
N.A.
0
86.6
N.A.
6.6
13.3
0
6.6
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
93.3
26.6
100
N.A.
13.3
93.3
N.A.
33.3
26.6
13.3
20
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
8
8
8
0
0
8
0
0
16
8
0
8
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
31
0
8
% C
% Asp:
0
39
8
0
0
8
0
0
0
0
8
0
16
8
0
% D
% Glu:
0
16
8
8
0
0
0
16
8
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
31
0
0
0
% F
% Gly:
31
0
8
24
8
8
16
0
0
8
16
8
16
8
0
% G
% His:
8
0
0
0
0
0
0
8
8
24
0
0
0
0
0
% H
% Ile:
0
8
16
0
0
8
8
8
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
39
31
0
0
8
0
8
0
8
0
8
% K
% Leu:
8
8
24
0
0
0
8
0
39
0
8
8
0
0
8
% L
% Met:
0
0
0
31
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
8
0
8
8
8
8
39
16
8
16
24
16
8
8
8
% N
% Pro:
16
8
0
0
0
8
8
0
8
0
0
0
8
0
8
% P
% Gln:
0
8
0
8
8
0
8
0
0
16
0
0
8
0
39
% Q
% Arg:
0
0
8
0
16
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
0
0
16
0
16
8
8
16
0
0
24
8
0
39
0
% S
% Thr:
8
8
0
8
0
0
8
0
8
0
8
8
0
0
0
% T
% Val:
0
8
0
0
0
8
0
0
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
31
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _